Quantity size:
0.2ml
Concentration:
1mg/ml线粒体促凋亡蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively. The inhibitor of apoptosis (IAP) 线粒体促凋亡蛋白抗体proteins regulate programmed cell death by inhibiting members of the caspase family of enzymes. A novel mammalian protein that binds to IAPs and neutralizes their inhibitory effect on caspases has been designated Smac/DIABLO. This is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates the cytochrome c/Apaf-1/caspase-9 pathway. Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases. Smac/DIABLO is expressed in a variety of human and mouse tissues.
线粒体促凋亡蛋白抗体Also known as:
Smac / Diablo; 0610041G12Rik; DBLOH_HUMAN; DBOH; DBOH; diablo; Diablo homolog (Drosophila); Diablo homolog (Drosophila); Diablo homolog; Diablo homolog Drosophila; Diablo homolog mitochondrial; Diablo homolog mitochondrial precursor; DIABLO S; DIABLO S; DIABLOS; Direct IAP binding protein with low pI; Direct IAP-binding protein with low pI; FLJ10537; FLJ25049; mitochondrial; Mitochondrial Smac protein; Second Mitochondria 线粒体促凋亡蛋白抗体Derived Activator of Caspase; Second mitochondria-derived activator of caspase; SMAC 3; smac; Smac protein; SMAC3.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, .
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Immunogen: KLH conjugated synthetic peptide derived from human Smac.
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线粒体促凋亡蛋白抗体Predicted Molecular Weight: 21kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl022Ga01血管内皮细胞蛋白C受体(PROCR)多克隆抗体Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Hu01血管内皮细胞蛋白C受体(PROCR)多克隆抗体Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Mu01血管内皮细胞蛋白C受体(PROCR)多克隆抗体Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Po01血管内皮细胞蛋白C受体(PROCR)多克隆抗体Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Ra01血管内皮细胞蛋白C受体(PROCR)多克隆抗体Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl024Bo01内分泌腺来源血管内皮生长因子(EG-VEGF)多克隆抗体Polyclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF)
kl024Hu01内分泌腺来源血管内皮生长因子(EG-VEGF)多克隆抗体Polyclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF)
kl024Mu01内分泌腺来源血管内皮生长因子(EG-VEGF)多克隆抗体Polyclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF)
kl024Ra01内分泌腺来源血管内皮生长因子(EG-VEGF)多克隆抗体Polyclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF)
kl025Bo01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
kl025Eq01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
kl025Gu01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
kl025Hu01嗜酸粒细胞趋化因子(ECF)多克隆抗体Polyclonal Antibody to Eosinophil Chemotactic Factor (ECF)
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更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
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