髓细胞/淋巴细胞或混合谱系白血病蛋白6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 髓细胞/淋巴细胞或混合谱系白血病蛋白6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10% of patients with acute lymphoblastic leukemia (ALL) and 5% of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. The gene encoding MLLT6, also known as mixed-lineage leukemia髓细胞/淋巴细胞或混合谱系白血病蛋白6抗体 translocated to 6 or AF17, is located on chromosome 17q12 and encodes a 1093 amino acid protein that is thought to be involved in the translocations on chromosome 11q23. Localized to the nucleus, MLLT6 contains a leucine-zipper dimerization motif located 3-prime of the fusion point and a cysteine-rich domain at the C-terminus. MLLT6 is thought to play a role in ALL by repressing the activity of the truncated ALL1 protein.

髓细胞/淋巴细胞或混合谱系白血病蛋白6抗体Also known as:

AF 17; AF17; AF17_HUMAN; ALL1-fused gene from chromosome 17 protein; FLJ23480; MLLT 6; MLLT6; Myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog) translocated to 6; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila) translocated to 6; Myeloid/lymphoid or mixed lineage leukemia translocated to 6; OTTHUMP00000164158; Protein AF 17; Protein AF-17; Trithorax homolog.

Specificity:

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Rabbit Polyclonal IgG, 髓细胞/淋巴细胞或混合谱系白血病蛋白6抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, .

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Immunogen: KLH conjugated synthetic peptide derived from human MLLT6.

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Predicted Molecular Weight: 125kDa.

髓细胞/淋巴细胞或混合谱系白血病蛋白6抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user

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