5甲基胞嘧啶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 5甲基胞嘧啶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), 5甲基胞嘧啶抗体a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.

5甲基胞嘧啶抗体Also known as:

5-Methyl Cytidine; 5 m C; 5 mC; 5 me C; 5 Me Cytidine; 5 MeCyd; 5 Methyl Cytidine; 5 MethylCytosine; 5-mC; 5-Me Cytidine; 5-Methyl-Cytosine; 5-MethylCytidine.

Specificity:

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Rabbit Polyclonal IgG,5甲基胞嘧啶抗体 affinity purified by Protein A.

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Reacts with: 5 MethylCytosine.

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Immunogen: KLH conjugated 5 MethylCytosine.

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Predicted Molecular Weight: 0.16159kDa.

5甲基胞嘧啶抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  ICC=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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