层粘蛋白α3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 层粘蛋白α3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin 5 is an isoform composed of three distinct subunits, alpha 3, beta 3 and gamma 2, which are bound to each other in a cross-shaped 层粘蛋白α3抗体molecule by disulphide bonds. It is a complex glycoprotein thought to be involved in cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes. It is also involved in signal transduction via tyrosine phosphorylation of pp125-FAK and p80, and differentiation of keratinocytes. 
The laminin alpha 3 subunit is also thought to be a component of laminin 6 and laminin 7.

层粘蛋白α3抗体Also known as:

Laminin alpha 3; LAMA3; LAMNA; Laminin subunit alpha-3; Laminin-5 subunit alpha; Laminin 5 alpha 3; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Epiligrin 170 kDa subunit; E170; Epiligrin subunit alpha; Kalinin subunit alpha; Nicein subunit alpha, BM600; LOCS; LAMA3_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, 层粘蛋白α3抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human LAMA3.

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Predicted Molecular Weight: 190(human, rat)3kDa.

层粘蛋白α3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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