Kelch样蛋白2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml Kelch样蛋白2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

KLHL2 is a 593 amino acid actin-binding protein. Highly expressed in brain, KLHL2 is thought to play a role in the organization of the actin cytoskeleton in brain cells. KLHL3 (kelch-like protein 3), is a 587 amino acid protein active in the protein ubiquitination pathway. KLHL3 is thought to be a substrate-specific adapter of an E3 ubiquitin-ligase complexKelch样蛋白2抗体 that mediates the ubiquitination of target proteins, which leads to proteasomal degradation of the target protein. KLHL2 and KLHL3 proteins contain six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multipleKelch样蛋白2抗体 copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.

Also known as:

ABP KELCH; Actin binding protein Mayven; Actin-binding protein Mayven; kelch; kelch like 2; Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN; OTTHUMP00000219997; OTTHUMP00000219998.

Specificity:

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Rabbit Polyclonal IgG,Kelch样蛋白2抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human KLHL2.

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Predicted Molecular Weight: 66kDa.

Kelch样蛋白2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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