Quantity size:
0.2ml
Concentration:
1mg/ml激肽释放酶8抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Kallikrein 8 (hK8), also known as neuropsin, brain serine protease 1 (BSP1), tumor associated differentially expressed gene 14 (TADG14), PRSS19, HNP and ovasin, is a trypsin like serine protease. Originally described from mouse brain, KLK8 was implicated in neural plasticity and learning. Kallikrein 8 is thought to be involved in neurite outgrowth and fasciculation during nervous system development. Kallikrein 8 is induced in neurite injury, and Kallikrein 8 has been shown to be elevated in the hippocampus on Alzheimer’s patients’ brains. Animal models of autoimmune encephalomyelitis (EAE) 激肽释放酶8抗体show elevated Kallikrein 8 production. Kallikrein 8 null mice have aberrant synapses in their hippocampus, compared to wild type mice, and are predisposed to seizures. Kallikrein 8 is thought to regulate the early phase of long-term potentiation (LTP), possibly by cleaving fibronectin and other substrates. Kallikrein 8 is also found in the uterus, where it is hormonally regulated. Cervical cancer cell lines express high levels of Kallikrein 8,激肽释放酶8抗体 and it may be useful as a tumor marker. Kallikrein 8 is not limited to the brain and uterus, as many tissues and cell lines make the protein. Endogenous inhibitors include serine protease inhibitor 3 and protein C inhibitor, although Kallikrein 8 can be found complexed to a number of different protease inhibitors.
Also known as:
Kallikrein-8; Ovasin; Serine protease TADG 14; Tumor associated differentially expressed gene 14 protein; Brain serine protease 1; BSP1; hK8; HNP; HPN; Kallikrein 8 (neuropsin/ovasin); Kallikrein related peptidase 8; Kallikrein8; KLK 8; KLK8; KLK-8; KLK8 protein type 1; KLK8 protein type 2; Neuropsin; neuropsin type 1; Neuropsin type 1, included; Neuropsin type 2; Neuropsin type 2, included; Neuropsin, mouse, homolog of;激肽释放酶8抗体 NP; NRPN; Protease serine 19; PRSS 19; PRSS19; Serine protease 19; Serine protease kallikrein; Serine protease kallikrein/ovasin/neuropsin; Serine protease TADG14; TADG 14; TA
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig, .
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Immunogen: KLH conjugated synthetic peptide derived from human KLK8.
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激肽释放酶8抗体Predicted Molecular Weight: 25kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl302Mu01野鼠色基因相关蛋白(AGRP)多克隆抗体Polyclonal Antibody to Agouti Related Protein (AGRP)
kl302Ra01野鼠色基因相关蛋白(AGRP)多克隆抗体Polyclonal Antibody to Agouti Related Protein (AGRP)
kl303Hu01集聚蛋白(AGRN)多克隆抗体Polyclonal Antibody to Agrin (AGRN)
kl305Hu01补体成分4b(C4b)多克隆抗体Polyclonal Antibody to Complement Component 4b (C4b)
kl305Mu01补体成分4b(C4b)多克隆抗体Polyclonal Antibody to Complement Component 4b (C4b)
kl309Hu01多效生长因子(PTN)多克隆抗体Polyclonal Antibody to Pleiotrophin (PTN)
kl310Hu01弹性蛋白酶4(ELA4)多克隆抗体Polyclonal Antibody to Elastase 4 (ELA4)
kl310Mu01弹性蛋白酶4(ELA4)多克隆抗体Polyclonal Antibody to Elastase 4 (ELA4)
kl311Mu01阿黑皮素原(POMC)多克隆抗体Polyclonal Antibody to Proopiomelanocortin (POMC)
kl312Hu01分泌性白细胞蛋白酶抑制因子(SLPI)多克隆抗体Polyclonal Antibody to Secretory Leukocyte Peptidase Inhibitor (SLPI)
kl312Mu01分泌性白细胞蛋白酶抑制因子(SLPI)多克隆抗体Polyclonal Antibody to Secretory Leukocyte Peptidase Inhibitor (SLPI)
kl313Hu01整合素α1(ITGα1)多克隆抗体Polyclonal Antibody to Integrin Alpha 1 (ITGa1)
kl313Mu01整合素α1(ITGα1)多克隆抗体Polyclonal Antibody to Integrin Alpha 1 (ITGa1)
kl314Hu01谷胱甘肽还原酶(GR)多克隆抗体Polyclonal Antibody to Glutathione Reductase (GR)
kl314Ra01谷胱甘肽还原酶(GR)多克隆抗体Polyclonal Antibody to Glutathione Reductase (GR)
kl316Hu01前胶原C端蛋白酶增强子1(PCPE1)多克隆抗体Polyclonal Antibody to Procollagen C Proteinase Enhancer 1 (PCPE1)
kl316Mu01前胶原C端蛋白酶增强子1(PCPE1)多克隆抗体Polyclonal Antibody to Procollagen C Proteinase Enhancer 1 (PCPE1)
kl317Hu01穿孔素1(PRF1)多克隆抗体Polyclonal Antibody to Perforin 1 (PRF1)
kl317Mu01穿孔素1(PRF1)多克隆抗体Polyclonal Antibody to Perforin 1 (PRF1)
kl317Ra01穿孔素1(PRF1)多克隆抗体Polyclonal Antibody to Perforin 1 (PRF1)
kl319Hu01微管关联蛋白4(MAP4)多克隆抗体Polyclonal Antibody to Microtubule Associated Protein 4 (MAP4)
kl319Ra01微管关联蛋白4(MAP4)多克隆抗体Polyclonal Antibody to Microtubule Associated Protein 4 (MAP4)
kl320Hu01胸腺基质淋巴细胞生成素(TSLP)多克隆抗体Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP)
kl320Mu01胸腺基质淋巴细胞生成素(TSLP)多克隆抗体Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP)
kl320Ra01胸腺基质淋巴细胞生成素(TSLP)多克隆抗体Polyclonal Antibody to Thymic Stromal Lymphopoietin (TSLP)
kl323Hu01钙调磷酸酶(CaN)多克隆抗体Polyclonal Antibody to Calcineurin (CaN)
kl323Ra01钙调磷酸酶(CaN)多克隆抗体Polyclonal Antibody to Calcineurin (CaN)
kl326Hu01神经丝蛋白3(NEF3)多克隆抗体Polyclonal Antibody to Neurofilament 3 (NEF3)
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企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
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上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
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