Quantity size:
0.2ml
Concentration:
1mg/ml 免疫球蛋白重链基因位点抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. This region represents the germline organization of the heavy chain locus. The locus includes V (variable), D (diversity), 免疫球蛋白重链基因位点抗体 J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single D segment with a J segment; this partially rearranged D-J gene is then joined to a V segment. The rearranged V-D-J is then transcribed with the IGHM constant region; this transcript encodes a mu heavy chain. Later in development B cells generate V-D-J-Cmu-Cdelta pre-messenger RNA, which is alternatively spliced to encode either a mu or a delta heavy chain. Mature B cells in the lymph nodes undergo switch recombination, so that the V-D-J gene is brought in proximity to one of the IGHG,免疫球蛋白重链基因位点抗体 IGHA, or IGHE genes and each cell expresses either the gamma, alpha, or epsilon heavy chain. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Due to polymorphism, the numbers of functional V, J, and D genes differ among individuals and some V, D, J, and C segments may be pseudogenes. [provided by RefSeq, Oct 2013]
Also known as:
IGH; IGH.1@; IGHDY1; Immunoglobulin heavy locus.
免疫球蛋白重链基因位点抗体 Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated synthetic peptide derived from human IGH.
●
免疫球蛋白重链基因位点抗体 Predicted Molecular Weight: 37kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
l699Hu01环加氧酶2(PTGS2)多克隆抗体Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 2 (PTGS2)
kl699Mu01环加氧酶2(PTGS2)多克隆抗体Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 2 (PTGS2)
kl699Ra01环加氧酶2(PTGS2)多克隆抗体Polyclonal Antibody to Prostaglandin Endoperoxide Synthase 2 (PTGS2)
kl700Hu01棕榈酰化膜蛋白6(MPP6)多克隆抗体Polyclonal Antibody to Membrane Protein, klmitoylated 6 (MPP6)
kl702Pl01硫氧化还原蛋白(Trx)多克隆抗体Polyclonal Antibody to Thioredoxin (Trx)
kl703Hu01硫氧还蛋白还原酶1(TrxR1)多克隆抗体Polyclonal Antibody to Thioredoxin Reductase 1 (TrxR1)
kl703Mu01硫氧还蛋白还原酶1(TrxR1)多克隆抗体Polyclonal Antibody to Thioredoxin Reductase 1 (TrxR1)
kl704Po01载脂蛋白E(APOE)多克隆抗体Polyclonal Antibody to Apolipoprotein E (APOE)
kl704Rb51载脂蛋白E(APOE)多克隆抗体Polyclonal Antibody to Apolipoprotein E (APOE)
kl706Hu01内脏脂肪特异性丝氨酸蛋白酶抑制因子(Vaspin)多克隆抗体Polyclonal Antibody to Visceral Adipose Tissue Derived Serine Protease Inhibitor (Vaspin)
kl706Mu01内脏脂肪特异性丝氨酸蛋白酶抑制因子(Vaspin)多克隆抗体Polyclonal Antibody to Visceral Adipose Tissue Derived Serine Protease Inhibitor (Vaspin)
kl706Ra01内脏脂肪特异性丝氨酸蛋白酶抑制因子(Vaspin)多克隆抗体Polyclonal Antibody to Visceral Adipose Tissue Derived Serine Protease Inhibitor (Vaspin)
kl708Hu01δ-促睡眠肽(δSIP)多克隆抗体Polyclonal Antibody to Delta-Sleep Inducing Peptide (dSIP)
kl709Hu01Toll样受体9(TLR9)多克隆抗体Polyclonal Antibody to Toll Like Receptor 9 (TLR9)
kl711Hu01肝素酶(HPA)多克隆抗体Polyclonal Antibody to Heklanase (HPA)
kl711Mu01肝素酶(HPA)多克隆抗体Polyclonal Antibody to Heklanase (HPA)
kl712Mu01钠/钾离子转运ATP酶β3肽(ATP1β3)多克隆抗体Polyclonal Antibody to ATkle, Na+/K+ Transporting Beta 3 Polypeptide (ATP1b3)
kl713Hu01CCAAT增强子结合蛋白β(CEBPβ)多克隆抗体Polyclonal Antibody to CCAAT/Enhancer Binding Protein Beta (CEBPb)
kl716Hu01葡萄糖6磷酸脱氢酶(G6PD)多克隆抗体Polyclonal Antibody to Glucose 6 Phosphate Dehydrogenase (G6PD)
kl716Ra01葡萄糖6磷酸脱氢酶(G6PD)多克隆抗体Polyclonal Antibody to Glucose 6 Phosphate Dehydrogenase (G6PD)
kl717Hu01次黄嘌呤磷酸核糖基转移酶1(HPRT1)多克隆抗体Polyclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1)
kl717Mu01次黄嘌呤磷酸核糖基转移酶1(HPRT1)多克隆抗体Polyclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1)
kl718Hu01β-位淀粉样前体蛋白裂解酶1(βACE1)多克隆抗体Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1)
kl718Mu01β-位淀粉样前体蛋白裂解酶1(βACE1)多克隆抗体Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1)
kl718Ra01β-位淀粉样前体蛋白裂解酶1(βACE1)多克隆抗体Polyclonal Antibody to Beta-Site APP Cleaving Enzyme 1 (bACE1)
kl721Hu01C-型钠尿肽(CNP)多克隆抗体Polyclonal Antibody to C-Type Natriuretic Peptide (CNP)
kl721Mu01C-型钠尿肽(CNP)多克隆抗体Polyclonal Antibody to C-Type Natriuretic Peptide (CNP)
更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
客服电话