Quantity size:
0.2ml
Concentration:
1mg/ml 胰岛素诱导基因1抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element binding protein (SREBP) mediated signaling pathway. Insig1 is an insulin-induced gene.胰岛素诱导基因1抗体 It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. It may also play a role in growth and differentiation 胰岛素诱导基因1抗体of tissues involved in metabolic control, and may play a regulatory role during G0/G1 transition of cell growth.
VAlso known as:
CL 6; CL6; INSIG 1; INSIG 1 membrane protein; INSIG1 membrane protein; Insulin induced gene 1; Insulin induced gene 1 protein; insulin induced gene-1; insulin induced gene1; MGC1405; INSI1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human Insig1.
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VPredicted Molecular Weight: 30kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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