同源盒蛋白D12抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 同源盒蛋白D12抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The Hox (homeobox) genes play an important role in the development and design of anterior-posterior body axes in animals. Although Hox proteins can bind to DNA as monomers, dimerization with PBX homeoproteins can significantly increase the DNA binding activity of these transcription factors. The HoxD9 gene is involved in the development and patterning of 同源盒蛋白D12抗体the forelimb and axial skeleton. Transcriptional activation of HoxD9 has been shown to be enhanced by HMG1 (high mobility group protein 1) and antagonized by HoxD8, suggesting that Hox protein function depends on both DNA-protein and protein-protein interactions. The HOX genes are known to regulate 同源盒蛋白D12抗体a number of cell adhesion molecules (CAMs), with HoxD9 specifically increasing levels of L-CAM transcripts. In presomitic mesoderm, HoxD1 displays dynamic stripes of expression. In the three stages of diencephalon development, HoxD1 is strongly expressed in the first two stages and downregulated in the third stage.

Also known as:

Homeobox protein Hox D12; Homeobox protein Hox-4H; Homeobox protein Hox-D12; Hox 4.7, mouse, homolog of; 同源盒蛋白D12抗体Hox 4H; HOX4H; HOXD12; HXD12_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from human HOXD12.

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Predicted Molecular Weight: 30kDa.

同源盒蛋白D12抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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