疱疹病毒相关泛素特异性蛋白酶7抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  疱疹病毒相关泛素特异性蛋白酶7抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression疱疹病毒相关泛素特异性蛋白酶7抗体 and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection.

疱疹病毒相关泛素特异性蛋白酶7抗体Also known as:

Deubiquitinating enzyme 7; herpes virus associated; Herpes virus associated ubiquitin specific protease; Herpesvirus-associated ubiquitin-specific protease; TEF 1; tef-1; TEF1; Ubiquitin carboxyl terminal hydrolase 7; Ubiquitin carboxyl-terminal hydrolase 7; Ubiquitin specific peptidase 7 (herpes virus associated); Ubiquitin specific peptidase 7; Ubiquitin specific peptidase 7 herpes virus associated; Ubiquitin specific疱疹病毒相关泛素特异性蛋白酶7抗体 processing protease 7; Ubiquitin Specific Protease 7; Ubiquitin specific protease 7 herpes virus associated; Ubiquitin thioesterase 7; ubiquitin thiolesterase 7; Ubiquitin-spec

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human HAUSP/US.

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疱疹病毒相关泛素特异性蛋白酶7抗体Predicted Molecular Weight: 128kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl075Hu01促胰液素(SCT)多克隆抗体Polyclonal Antibody to Secretin (SCT)

kl075Mu01促胰液素(SCT)多克隆抗体Polyclonal Antibody to Secretin (SCT)

kl077Hu01ⅡD组磷脂酶A2(PLA2G2D)多克隆抗体Polyclonal Antibody to Phospholikle A2, Group IID (PLA2G2D)

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