Quantity size:
0.2ml
Concentration:
1mg/ml 丙型肝炎病毒-NS3抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation丙型肝炎病毒-NS3抗体 leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates丙型肝炎病毒-NS3抗体 apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
丙型肝炎病毒-NS3抗体Also known as:
HCV-NS3; Serine protease NS3; Hepacivirin; NS3P; POLG_HCVBK; HCV NS3 transactivated protein; Hepatitis C Virus NS3; non structural polyprotein NS3; NS3; NS3P; Serine protease/NTPase/helicase. helicase NS3; NS3P; p70; NTPase; Serine protease.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Hepatitis C Virus.
●
Immunogen: KLH conjugated synthetic peptide derived from HCV-NS3.
●
Predicted Molecular Weight: 69kDa.
丙型肝炎病毒-NS3抗体
kl050Mu01雌激素受体α(ERα)多克隆抗体Polyclonal Antibody to Estrogen Receptor Alpha (ERa)
kl050Ra01雌激素受体α(ERα)多克隆抗体Polyclonal Antibody to Estrogen Receptor Alpha (ERa)
kl051Hu01胆囊收缩素B受体(CCKBR)多克隆抗体Polyclonal Antibody to Cholecystokinin B Receptor (CCKBR)
kl053Hu01细胞色素P450家族成员7A1(CYP7A1)多克隆抗体Polyclonal Antibody to Cytochrome P450 7A1 (CYP7A1)
kl053Mu01细胞色素P450家族成员7A1(CYP7A1)多克隆抗体Polyclonal Antibody to Cytochrome P450 7A1 (CYP7A1)
kl054Hu01凋亡蛋白酶激活因子1(Akl1)多克隆抗体Polyclonal Antibody to Apoptotic Peptidase Activating Factor 1 (Akl1)
kl058Hu01胱天蛋白酶激活脱氧核糖核酸酶(CAD)多克隆抗体Polyclonal Antibody to Caskle Activated DNase (CAD)
kl059Hu01岩藻糖基转移酶4(FUT4)多克隆抗体Polyclonal Antibody to Fucosyltransferase 4 (FUT4)
kl061Hu01蛋白二硫键异构酶(PDI)多克隆抗体Polyclonal Antibody to Protein Disulfide Isomerase (PDI)
kl062Hu0170kDa热休克蛋白1样蛋白(HSPA1L)多克隆抗体Polyclonal Antibody to Heat Shock 70kDa Protein 1 Like Protein (HSPA1L)
kl063Hu01泛素结合酶E2A(UBE2A)多克隆抗体Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2A (UBE2A)
kl063Mu01泛素结合酶E2A(UBE2A)多克隆抗体Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2A (UBE2A)
kl064Hu01凋亡诱导因子(AIF)多克隆抗体Polyclonal Antibody to Apoptosis Inducing Factor (AIF)
kl064Ra01凋亡诱导因子(AIF)多克隆抗体Polyclonal Antibody to Apoptosis Inducing Factor (AIF)
kl065Hu01丙氨酸氨肽酶(AAP)多克隆抗体Polyclonal Antibody to Alanine Aminopeptidase (AAP)
kl066Hu01多巴色素异构酶(DT)多克隆抗体Polyclonal Antibody to Doklhrome Tautomerase (DCT)
kl067Hu01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)
kl067Mu01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)
kl067Ra01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)
kl068Hu01多药耐药关联蛋白1(MRP1)多克隆抗体Polyclonal Antibody to Multidrug Resistance Associated Protein 1 (MRP1)
kl070Ca01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Hu01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Mu01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Po01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Ra01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
客服电话