谷氨酸受体δ2/GluR-δ2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  谷氨酸受体δ2/GluR-δ2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Grid2ip is a postsynaptic scaffolding protein that contains one formin homology 2 (FH2) domain and two PDZ (postsynaptic density-95/discs-large/ZO-1) domains. Expressed in Purkinje cells of the cerebellum and localizing specifically to parallel fiber synapses,谷氨酸受体δ2/GluR-δ2抗体 Grid2ip interacts with the C-terminus of GluR-Delta 2 and, via this interaction, links GluR-Delta 2 with various signaling molecules and the Actin cytoskeleton. GluR-Delta 2 is a glutamate receptor with an important role in motor learning, cerebellar wiring and synaptic plasticity. Due to alternative splicing events, three Grid2ip isoforms exist, namely L-delphilin, S-delphilin (or delphilin-Alpha) and delphilin-Beta. Each isoform exhibits individual expression patterns and protein interactions. Isoform 2, delphilin-Alpha, is palmytoylated, 谷氨酸受体δ2/GluR-δ2抗体a modification that is essential for the enhanced expression of GluR-Delta 2 on the cell surface. This modification of delphilin-Alpha also mediates the accumulation of delphilin-Alpha in dendritic spines.

谷氨酸受体δ2/GluR-δ2抗体Also known as:

Delphilin; delta 2 interacting protein 1; Grid Delta2; GluR-Delta 2 Glutamate receptor; GRD2I_HUMAN; grid2ip; ionotropic.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human GRID2IP.

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谷氨酸受体δ2/GluR-δ2抗体Predicted Molecular Weight: 132kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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