细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Prostate cancer is the most frequently diagnosed cancer and the early detection of prostate cancer dramatically and efficiently reduces the observed mortality rate. Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer,细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体 PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Conversely, STEAP (six-transmembrane epithelial antigen of the prostate), prostate carcinoma tumor antigen (PCTA-1) and prostate-specific membrane antigen (PSM) represent additional prostate-specific antigens that are overexpressed only in malignant tumors and therefore are more specific identifiers of malignancies. PSM is an integral membrane protein, and PCTA-1 is related to the galectin gene family, which mediate both cell-cell and cell-matrix interactions in a manner similar to细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体 the selectin subgroup of C-type lectins. STEAP is a serpentine transmembrane cell-surface tumor-antigen that is predicted to functions as a channel or transporter protein. In addition to prostate cancers, STEAP is also upregulated in bladder, colon and ovarian cancers.

Also known as:

PSMAL; Cell growth inhibiting gene 26 protein; Folate hydrolase 1B; Folate hydrolase 2; Folate hydrolase pseudogene; FOLH2; FOLHP; GCP3; GCPIII; glutamate carboxypeptidase III; N acetylated alpha linked acidic dipeptidase; NAALADase; Prostate specific membrane 细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体antigen like protein; PSM; PSMA like; Putative folate hydrolase 1B; Putative N acetylated alpha linked acidic dipeptidase; FOH1B_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human FOLH1B (.

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Predicted Molecular Weight: 50kDa.

细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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