核酸内切酶结构域蛋白1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 核酸内切酶结构域蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ENDOD1 is a 500 amino acid secreted protein that belongs to the DNA/RNA non-specific endonuclease family. ENDOD1 is thought to act as a DNase and an RNase. The gene that encodes ENDOD1 maps to human chromosome 11, which comprises approximately 4% of human genomic核酸内切酶结构域蛋白1抗体 DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors,核酸内切酶结构域蛋白1抗体 WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

核酸内切酶结构域蛋白1抗体Also known as:

C85344; ENDD1_HUMAN; ENDOD1; Endonuclease domain containing 1; Endonuclease domain-containing 1 protein; KIAA0830.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human ENDOD1.

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Predicted Molecular Weight: 53kDa.

核酸内切酶结构域蛋白1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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