Quantity size:
0.2ml
Concentration:
1mg/ml桥粒斑蛋白1+2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Desmosomes are intercellular junctions that form tight links between adjacent cells. Desmoplakin is an obligate component of functional desmosomes that attaches intermediate filaments to desmosomal plaques. It is involved in the organization of desmosomal cadherin-plakoglobin complexes桥粒斑蛋白1+2抗体 into discrete plasma membrane domains. The N-terminus of desmoplakin is essential for localisation to the desmosome and interaction with plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds to intermediate filaments. The central region of desmoplakin comprises a coiled-coil rod domain that mediates homodimerisation. There are two isoforms 桥粒斑蛋白1+2抗体of desmoplakin - desmoplakin I, which is an obligate component of all desmosomes, and desmoplakin II, which is predominantly expressed in tissues and cells of stratified origin. Mutations in the gene encoding desmoplakin result in a number of cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
Also known as:
桥粒斑蛋白1+2抗体250/210 kDa paraneoplastic pemphigus antigen; Desmoplakin (DPI DPII); Desmoplakin; Desmoplakin I; Desmoplakin II; DESP_HUMAN; DP; DP I; DP II; DPI; DPII; DSP; KPPS2; PPKS 2; PPKS2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human DP-I.
●
桥粒斑蛋白1+2抗体Predicted Molecular Weight: 331kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl662Mu01白介素7(IL7)多克隆抗体Polyclonal Antibody to Interleukin 7 (IL7)
kl662Ra01白介素7(IL7)多克隆抗体Polyclonal Antibody to Interleukin 7 (IL7)
kl663Hu01Toll样受体2(TLR2)多克隆抗体Polyclonal Antibody to Toll Like Receptor 2 (TLR2)
kl663Mu01Toll样受体2(TLR2)多克隆抗体Polyclonal Antibody to Toll Like Receptor 2 (TLR2)
kl663Ra01Toll样受体2(TLR2)多克隆抗体Polyclonal Antibody to Toll Like Receptor 2 (TLR2)
kl668Hu01血管生成素4(ANGPT4)多克隆抗体Polyclonal Antibody to Angiopoietin 4 (ANGPT4)
kl669Hu01激肽释放酶11(KLK11)多克隆抗体Polyclonal Antibody to Kallikrein 11 (KLK11)
kl670Mu01归巢关联细胞黏附分子(HCAM)多克隆抗体Polyclonal Antibody to Homing Associated Cell Adhesion Molecule (HCAM)
kl671Ra01谷胱甘肽S转移酶α3(GSTα3)多克隆抗体Polyclonal Antibody to Glutathione S Transferase Alpha 3 (GSTa3)
kl672Hu01Slit同源物2(Slit2)多克隆抗体Polyclonal Antibody to Slit Homolog 2 (Slit2)
kl672Mu01Slit同源物2(Slit2)多克隆抗体Polyclonal Antibody to Slit Homolog 2 (Slit2)
kl672Ra01Slit同源物2(Slit2)多克隆抗体Polyclonal Antibody to Slit Homolog 2 (Slit2)
kl673Ca01多巴胺受体D2(DRD2)多克隆抗体Polyclonal Antibody to Dokline Receptor D2 (DRD2)
kl673Hu01多巴胺受体D2(DRD2)多克隆抗体Polyclonal Antibody to Dokline Receptor D2 (DRD2)
kl675Hu01凝血因子Ⅴ(F5)多克隆抗体Polyclonal Antibody to Coagulation Factor V (F5)
kl675Mu01凝血因子Ⅴ(F5)多克隆抗体Polyclonal Antibody to Coagulation Factor V (F5)
kl675Ra01凝血因子Ⅴ(F5)多克隆抗体Polyclonal Antibody to Coagulation Factor V (F5)
kl677Hu01凝血因子Ⅻ(F12)多克隆抗体Polyclonal Antibody to Coagulation Factor XII (F12)
kl677Mu01凝血因子Ⅻ(F12)多克隆抗体Polyclonal Antibody to Coagulation Factor XII (F12)
kl680Hu01棕榈酰化膜蛋白2(MPP2)多克隆抗体Polyclonal Antibody to Membrane Protein, klmitoylated 2 (MPP2)
kl680Ra01棕榈酰化膜蛋白2(MPP2)多克隆抗体Polyclonal Antibody to Membrane Protein, klmitoylated 2 (MPP2)
kl681Hu01乙醇脱氢酶1(ADH1)多克隆抗体Polyclonal Antibody to Alcohol Dehydrogenase 1 (ADH1)
更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
客服电话