双氧化酶1/甲状腺氧化酶1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 双氧化酶1/甲状腺氧化酶1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid,双氧化酶1/甲状腺氧化酶1抗体  trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.

双氧化酶1/甲状腺氧化酶1抗体 Also known as:

Dual oxidase 1; Dual oxidase 1 precursor; DUOX1; EC 1.11.1; EC 1.6.3.1; Flavoprotein NADPH oxidase; Large NOX 1; LNOX1; Long NOX 1; MGC138840; MGC138841; NADPH thyroid oxidase 1; Nicotinamide adenine dinucleotide phosphate oxidase; NOXEF1; THOX1; Thyroid oxidase 1; DUOX1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, 双氧化酶1/甲状腺氧化酶1抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human DUOX1 (1.

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双氧化酶1/甲状腺氧化酶1抗体 Predicted Molecular Weight: 175kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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