1号染色体开放阅读框173抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 1号染色体开放阅读框173抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably,1号染色体开放阅读框173抗体 the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.1号染色体开放阅读框173抗体 A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf173 gene product has been provisionally designated C1orf173 pending further characterization. There are three isoforms of C1orf173 that are produced as a result of alternative splicing events.

1号染色体开放阅读框173抗体Also known as:

C1orf173; CA173_HUMAN; Chromosome 1 open reading frame 173; DKFZp547I048; DKFZp761G1720; DKFZp781L0319; Hypothetical protein LOC127254; MGC90412; OTTHUMP00000011196; RP11-653A5.1; Uncharacterized protein C1orf173.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human C1orf173 .

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1号染色体开放阅读框173抗体Predicted Molecular Weight: 168kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

IHC-P=1:100-500  IHC-F=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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