细胞粘附分子相关蛋白/癌基因下调蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 细胞粘附分子相关蛋白/癌基因下调蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells.细胞粘附分子相关蛋白/癌基因下调蛋白抗体 CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch.细胞粘附分子相关蛋白/癌基因下调蛋白抗体 The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.

Also known as:

CDO; CDON; Cell adhesion molecule-related/down-regulated by oncogenes; CDON_HUMAN.

细胞粘附分子相关蛋白/癌基因下调蛋白抗体Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human CDON.

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细胞粘附分子相关蛋白/癌基因下调蛋白抗体Predicted Molecular Weight: 136kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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