Quantity size:
0.1ml
Concentration:
1mg/ml 磷酸化p21蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.磷酸化p21蛋白抗体 This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. Two families of cyclin dependent kinase inhibitors (CKIs) have been identified. The p21WAF1/Cip1 family inhibits all kinases involved in the G1/S transition. The p16INK4a family inhibits Cdk4 and Cdk6 specifically.
磷酸化p21蛋白抗体Also known as:
Activating Fragment 1; CAP20; Cation chloride cotransporter-interacting protein 1; CDK Interacting Protein 1; CDK-interacting protein 1; CDKI; CDKN 1; CDKN1; CDKN1A; CIP1; Cyclin Dependent Kinase Inhibitor 1A; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1A (P21); Cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA Synthesis Inhibitor; MDA 6; MDA-6; MDA6; Melanoma Differentiation Associated Protein 6; Melanoma differentiation-associated protein 6; Melanoma differentiation-associated protein; p21; P21 protein; 磷酸化p21蛋白抗体p21CIP1; p21WAF; PIC1; SDI1; SLC12A9; WAF1; Wildtype p53 Activating Fragment 1; Wildtype p53-activated fragment 1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Dog, Pig, Cow, Sheep, Guinea Pig, G.
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CDKN1A around the phosphorylation site of Ser146 [QT(p-S)MT].
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磷酸化p21蛋白抗体Predicted Molecular Weight: 18kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl739Hu01周期素依赖性激酶5(CDK5)多克隆抗体Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)
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kl741Hu01Dickkopf相关蛋白1(DKK1)多克隆抗体Polyclonal Antibody to Dickkopf Related Protein 1 (DKK1)
kl741Ra01Dickkopf相关蛋白1(DKK1)多克隆抗体Polyclonal Antibody to Dickkopf Related Protein 1 (DKK1)
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kl746Hu01成纤维细胞生长因子23(FGF23)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 23 (FGF23)
kl746Mu01成纤维细胞生长因子23(FGF23)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 23 (FGF23)
kl746Ra01成纤维细胞生长因子23(FGF23)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 23 (FGF23)
kl748Hu01三叶因子2(TFF2)多克隆抗体Polyclonal Antibody to Trefoil Factor 2 (TFF2)
kl748Mu01三叶因子2(TFF2)多克隆抗体Polyclonal Antibody to Trefoil Factor 2 (TFF2)
kl750Hu01补体受体2(CR2)多克隆抗体Polyclonal Antibody to Complement Receptor 2 (CR2)
kl752Ra01环腺苷二磷酸核糖水解酶(cADPRH)多克隆抗体Polyclonal Antibody to Cyclic ADP Ribose Hydrolase (cADPRH)
kl753Bo01Toll样受体4(TLR4)多克隆抗体Polyclonal Antibody to Toll Like Receptor 4 (TLR4)
kl753Hu01Toll样受体4(TLR4)多克隆抗体Polyclonal Antibody to Toll Like Receptor 4 (TLR4)
kl753Mu01Toll样受体4(TLR4)多克隆抗体Polyclonal Antibody to Toll Like Receptor 4 (TLR4)
kl753Ra01Toll样受体4(TLR4)多克隆抗体Polyclonal Antibody to Toll Like Receptor 4 (TLR4)
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kl754Mu01肌球蛋白重链1(MYH1)多克隆抗体Polyclonal Antibody to Myosin Heavy Chain 1, Skeletal Muscle, Adult (MYH1)
kl755Mu01肌球蛋白重链2(MYH2)多克隆抗体Polyclonal Antibody to Myosin Heavy Chain 2, Skeletal Muscle, Adult (MYH2)
kl757Hu01表皮生长因子受体(EGFR)多克隆抗体Polyclonal Antibody to Epidermal Growth Factor Receptor (EGFR)
kl757Mu01表皮生长因子受体(EGFR)多克隆抗体Polyclonal Antibody to Epidermal Growth Factor Receptor (EGFR)
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企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
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