磷酸化周期素E抗体

?磷酸化周期素E抗体Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle.磷酸化周期素E抗体 Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

磷酸化周期素E抗体Also known as:

Cyclin E1 (phospho T395); p-Cyclin E1 (phospho T395); Cyclin E1 (phospho-Thr395); CCNE 1; CCNE;CCNE1;Cyclin E1 antibody Cyclin Es;Cyclin Et;CyclinE; G1/S specific cyclin E; CCNE1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG,磷酸化周期素E抗体 affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr395.

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磷酸化周期素E抗体Predicted Molecular Weight: 47kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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