乙酰基赖氨酸抗体Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
In the nucleus, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription. Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression. The acetylation of non-histone proteins such as transcription factors, 乙酰基赖氨酸抗体as well as histones appears to be involved in this process. Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain. Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation. The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and transcription, gene silencing,乙酰基赖氨酸抗体 cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. More than 20 acetyltransferases and 18 deacetylases have been identified so far, but the mechanistic details of substrate selection and site specificity of these enzymes remain unclear. Over 40 transcription factors and 30 other nuclear, cytoplasmic, bacterial, and viral proteins have been shown to be acetylated in vivo.
Also known as:
乙酰基赖氨酸抗体Ac-lysine; acetyl Lysine; Lysine.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Ac-lysine.
●
Immunogen: KLH conjugated synthetic peptide derived from human acetyl Lysine.
乙酰基赖氨酸抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl231Cp01尿皮质素1(UCN1)多克隆抗体Polyclonal Antibody to Urocortin 1 (UCN1)
kl231Hu01尿皮质素1(UCN1)多克隆抗体Polyclonal Antibody to Urocortin 1 (UCN1)
kl231Mu01尿皮质素1(UCN1)多克隆抗体Polyclonal Antibody to Urocortin 1 (UCN1)
kl231Ra01尿皮质素1(UCN1)多克隆抗体Polyclonal Antibody to Urocortin 1 (UCN1)
kl233Bo01蛋白激酶Cη(PKCη)多克隆抗体Polyclonal Antibody to Protein Kinase C Eta (PKCh)
kl233Hu01蛋白激酶Cη(PKCη)多克隆抗体Polyclonal Antibody to Protein Kinase C Eta (PKCh)
kl233Mu01蛋白激酶Cη(PKCη)多克隆抗体Polyclonal Antibody to Protein Kinase C Eta (PKCh)
kl233Ra01蛋白激酶Cη(PKCη)多克隆抗体Polyclonal Antibody to Protein Kinase C Eta (PKCh)
kl234Hu01免疫球蛋白G4(IgG4)多克隆抗体Polyclonal Antibody to Immunoglobulin G4 (IgG4)
kl235Hu01补体1抑制因子(C1INH)多克隆抗体Polyclonal Antibody to Complement 1 Inhibitor (C1INH)
kl235Mu01补体1抑制因子(C1INH)多克隆抗体Polyclonal Antibody to Complement 1 Inhibitor (C1INH)
kl235Ra01补体1抑制因子(C1INH)多克隆抗体Polyclonal Antibody to Complement 1 Inhibitor (C1INH)
kl235Rb51补体1抑制因子(C1INH)多克隆抗体Polyclonal Antibody to Complement 1 Inhibitor (C1INH)
kl238Hu01酪氨酸酶(TYR)多克隆抗体Polyclonal Antibody to Tyrosinase (TYR)
kl238Ra01酪氨酸酶(TYR)多克隆抗体Polyclonal Antibody to Tyrosinase (TYR)
kl243Hu01对氧磷酶1(PON1)多克隆抗体Polyclonal Antibody to klaoxonase 1 (PON1)
kl243Mu01对氧磷酶1(PON1)多克隆抗体Polyclonal Antibody to klaoxonase 1 (PON1)
更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
客服电话