?蛋白激酶B3Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity 蛋白激酶B3of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
蛋白激酶B3Also known as:
AKT3 kinase; DKFZP434N0250; PKB Gamma; PKBG; PRKBG; Protein Kinase AKT3; Protein Kinase B Gamma; RAC gamma; RAC Gamma Serine/Threonine Protein Kinase; RACPK Gamma; Serine threonine protein kinase Akt 3;蛋白激酶B3 Serine Threonine Protein Kinase AKT3; STK 2; STK2; V akt murine thymoma viral oncogene homolog 3 protein kinase B gamma; VAKT Murine Thymoma Viral Oncogene Homolog 3; AKT3_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human AKT3.
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Predicted Molecular Weight: 56kDa.
蛋白激酶B3Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:200-600 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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企业名称
上海康朗生物科技有限公司
企业信息已认证
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信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
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公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
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