芳香烃受体抗体

芳香烃受体抗体产品类别

 兔抗人、大、小鼠AHR抗体

克 隆 号

 浓缩液(1mg/1ml) 亲和纯化抗体

产品标准

 WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500

产品应用

 （石蜡切片需做抗原修复）

芳香烃受体抗体产品介绍

Chromatin and Nuclear Signaling (染色质和核信号)

Unlike the steroid/thyroid hormone receptors, there is no known physiological ligand for the AH Receptor. Studies indicate that in non-ligand activated cells, AHR is found complexed with HSP90 predominantly in the cytoplasm. Upon binding to an agonist, the ligand-activated AHR is believed to transform to a nuclear, DNA binding form. This transformation process appears to involve dissociation of HSP90 from AHR followed by formation of a heterodimer with AHR nuclear translocator protein (Arnt). The AHR-ligand complex appears to initiate gene transcription of cytochrome P450 1A1. 
     [SUBCELLULAR LOCATION] Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. 
     [TISSUE SPECIFICITY] Expressed in all tissues tested including brain, heart, kidney, liver, lung, muscle, ovary, skin, spleen and thymus. 
    mol wt:93kDa 
    Other Aliases: 
    aryl hydrocarbon receptor; Ah receptor; Aromatic hydrocarbon receptor; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor;BHLHE76; Class E basic helix loop helix protein 76; HGNC:348.

芳香烃受体抗体

hz-2138P PARP(poly ADP-ribose polymerase)N-Terminus  多腺苷二磷酸多聚酶抗原(N端)

hz-1201P PAX8(Paired box gene 8)  配对盒基因8抗原

hz-1102P PAX9(Paired box gene 9)  配对盒基因9抗原

hz-1159P P-cadherin(placental)  P-钙粘附分子抗原

hz-1617P LI-cadherin(liver-intestine cadherin)  肝肠钙粘连蛋白抗原

hz-1608P PDCD4(programmed cell death 4)  凋亡相关蛋白4抗原

hz-1333P TFAR19(TF-1 cell apoptsis-related gene 19)  凋亡相关蛋白TFAR19抗原

hz-2215P PCNA(phosphos Dyr211)peptide  磷酸化增殖细胞核多肽抗原

hz-1345P PCX/PODXL(Podocalyxin)  足细胞特异蛋白抗原

hz-1316P PDGF-BB peptide  血小板源性生长因子-BB抗原

hz-0923P Pdx1(pancreatic and duodenal homeobox 1)  胰十二指肠同源异型盒基因抗原

hz-2219P pectinesterase inhibitor 18 peptide  果胶酶抗原

hz-1084P PEG10(Paternally expressed gene 10)  肝癌高表达基因抗原

hz-2106P PENK/Enkephalin A(Preproencephalin A)  脑啡肽

hz-0584P PEPT2 (Peptide-transporters 2)  肠道肽转运蛋白2/小肽转运蛋白2抗原

hz-2469P PERK(PRKR-like endoplasmic reticulum kinase)  蛋白激酶R样内质网激酶抗原

hz-0796P FSCN1 (Fascin 1 protein; fascin homolog 1, actin-bundling protein)  纤维束蛋白同源物1/肌动蛋白集束蛋白/圆线虫紫癜 抗原

hz-0563P P-GP(P-glycoprotein)  P-糖蛋白抗原

hz-1551P Pepsinogen C peptide  胃蛋白酶原C蛋白抗原

hz-1832P PGC-1 Alpha(peroxisome proliferator-activated receptor- Gamma coactivator 1 Alpha)  过氧化物酶体增殖物激活受体γ辅激活子1α抗原

hz-0823P PGRN (progranulin)  颗粒蛋白前体抗原

hz-1449P PHB(Prohibitin)  抑制素/肿瘤抑制因子抗原

hz-0520P PKA(Protein Kinase A)  蛋白激酶A(多肽)

hz-1098P PLAU/uPA (Plasminogen activator,urokinase)  尿激酶型纤溶酶原激活因子（多肽）

hz-1048P Podoplanin Protein  平足蛋白抗原

hz-0891P Pokhzon (POK Erythroid Myeloid Ontogenic factor)  “扑克蒙”蛋白又称“波克曼”蛋白

hz-2157P Polycystin 1(Polycystic Kidney Disease 1)  多囊肾蛋白1抗原

hz-2158P Polycystin 2(polycystic kidney disease 2)  多囊肾蛋白2抗体

hz-0876P phospho-AKT1/PKB1/2/3(pThr473)peptide  磷酸化蛋白激酶B抗原（丝氨酸磷酸化位点：473）

hz-1436P RKIP(Raf kinase inhibitor protein)  Raf激酶抑制蛋白抗原

hz-2146P pre-X protein[Hepatitis B virus]N-Terminus  乙肝病毒pre-X蛋白抗原（N端）

hz-2147P pre-X protein(CT)[Hepatitis B virus C-Terminus]  乙肝病毒pre-X蛋白抗原（C端）

hz-0532P PHD3 (Egln3; HIF-prolyl hydroxylase 3)  脯氨酸羟化酶(多肽)

hz-0433P ADAMTS-7(a disintegrin-like and metalloprotease-7 )  新型金属基质蛋白酶(抗原)

hz-0471P Adiponectin  脂联素（多肽抗原）