生长因子受体结合蛋白2抗体产品类别
兔抗人、大、小鼠Grb2蛋白抗体
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
生长因子受体结合蛋白2抗体产品介绍
Growth factor receptor bound protein 2 (GRB2), also known as Ash protein, is a 24 kDa protein that contains a central Src homology (SH2) domain flanked by two SH3 domains. GRB2 is believed to be a regulatory subunit of signaling molecules whose activity is modulated by receptor binding. GRB2 associates with activated (tyrosine phosphorylated) EGFR and PDGFR via its SH2 domain as well as IRS1, SHC, and LNK through SH2 and SH3 domains. The SH3 domain binds to SOS, a guanine nucleotide exchange factor for Ras proteins. Endocytosis of activated EGFR requires the interaction of GRB2 with the GTP binding protein dynamin, a factor essential to the formation of endocytotic vesicle. It is ubiquitously expressed and several isoforms are produced by alternative splicing. On SDS PAGE, GRB2 has an apparent molecular weight of 28 kDa.
Also known as:
Growth factor receptor-bound protein 2; Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb3 3; Growth Factor Receptor Bound Protein 2; Growth factor receptor bound protein 3; HT027; MST084; MSTP084; OTTHUMP00000166096; OTTHUMP00000166097; OTTHUMP00000166098; Protein ASH; SEM5 ; SH2/SH3 adapter GRB2.
生长因子受体结合蛋白2抗体
hz-0685P SYK (Spleen tyrosine kinase) 非受体型酪氨酸激酶(抗原)
hz-0419P Tau protein 微管相关蛋白(抗原)
hz-0778P Thy-1/CD90 CD90(抗原)
hz-0632P Thioster-containing protein 1 硫酯包含蛋白-1(抗原)
hz-0640P TIGAR humen (TP53- induced glycolysis and apoptosis-regulator ) P53诱导糖酵解和凋亡调节因子蛋白(抗原)
hz-0418P TIMP-4(Tissue Inhibitor of Metalloproteinase-4) 金属蛋白酶组织抑制因子-4(抗原)
hz-0447P TPO(Thyroid Peroxidase) 甲状腺过氧化物酶(抗原)
hz-0460P TSHR (Thyroid stimulating hormone receptor) 促甲状腺素受体(抗原)
hz-0449P TSLP(Thymic stromal lymphopoietin isoform 1) 淋巴细胞生成素-1(抗原)
hz-0446P TTF-2(thyroid transcription factor 2;forkhead box E1) 甲状腺转录因子-2(抗原)
hz-0819P Tyrosinase 酪氨酸酶(多肽抗原)
hz-0603P OAT4L又称URAT1 (Urate Transporter 1) 尿酸盐重吸收转运子1 (抗原)
hz-0853P VAP1(vascular adhesion protein 1) 血管粘附蛋白1(多肽抗原)
hz-0756P Vimentin 波形蛋白(抗原)
hz-0479P VSIG4 (V-set and immunoglobulin domain-containing protein 4) VSIG4 T淋巴细胞负调节蛋白之一(抗原)
hz-0429P WNK4(Ser/Thr-protein kinase WNK4; protein kinase with no lysine 4; protein kinase, lysine –dficient 4) 一种新的丝氨酸/苏氨酸激酶家族成员的基因WNK4(多肽抗原)
hz-0628P ZNF300 (zinc finger protein ZNF300)- middle 锌指蛋白300(抗原)
hz-0625P ZNF268 (zinc finger protein ZNF268)- N-terminal (1a) 锌指脂蛋白-1a(抗原)
hz-0626P ZNF268 (zinc finger protein ZNF268)- middle (1b) 锌指脂蛋白-1b(抗原)
hz-0627P ZNF268 (zinc finger protein ZNF268)- middle (1c) 人锌指脂蛋白-1c(抗原)
hz-0480P IFN- Gamma(Interferon Gamma)Ag-mouse、rat 干扰素-γ多肽抗原(大、小鼠)
hz-0481P IFN- Gamma(Interferon Gamma)Human 干扰素-γ多肽抗原(人)
hz-0784P IFN- Beta (Interferon Beta)Anti-mouse,rat 干扰素-β抗原
hz-0787P IFN- Beta (Interferon Beta) human 干扰素-β抗原
hz-0669P PSCA 前列腺干细胞抗原
hz-1930P ADH/AVP peptide 抗利尿激素/血管升压素抗原(和肽素)
hz-4507P PRRSV M protein 猪蓝耳病病毒M蛋白
hz-4814P-HRP Newcastle disease virus/HRP 鸡新城疫疫苗(鸡瘟4型混合病毒)偶联辣根过氧化物酶
hz-0645P sIgA 大鼠分泌型IgA(抗原)
hz-0904PK Melamine/KLH 三聚氰胺与血蓝蛋白偶联物
hz-0904PB Melamine/BSA 三聚氰胺与牛血清白蛋白偶联物
hz-0904PA Melamine/OVA(ovalbumin) 三聚氰胺与鸡卵白蛋白偶联物
hz-0971PB chloramphenicol/BSA 氯霉素偶联牛血清白蛋白
hz-0971PA chloramphenicol/OVA 氯霉素偶联鸡卵白蛋白蛋白
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