丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体产品说明

    HtrA2/Omi是一种寡聚丝氨酸蛋白酶,存在于大部分的正常组织器官中,当细胞受到凋亡刺激时,HtrA2/Omi可由线粒体膜间隙(mitochondrial intermembrane space)释放进入细胞质中,导致出现大量的细胞凋亡性死亡, Omi/HtrA2 为促凋亡因子.

    Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP. 
    mol wt:50kDa 
    Other Aliases: 
    High temperature requirement protein a2; HTRA 2 ; HtrA like serine protease; HtrA serine peptidase 2; Omi stress regulated endoprotease; PARK 13; PARK13; Protease serine 25; PRSS 25; PRSS25; Serine protease 25; Serine protease HTRA2 mitochondrial; Serine protease htra2 mitochondrial precursor; Serine protease omi

丝氨酸蛋白酶/线粒体丝氨酸蛋白酶抗体

hz-1577R KLF13/RFLAT-1  肠道内富含的Kruppel样因子13

hz-0225R KLH  血蓝蛋白抗体

hz-0225M KLH  血蓝蛋白抗体

hz-1963R KLK1  激肽释放酶1抗体

hz-5868R KLK2  激肽释放酶2抗体

hz-1094R kappa Opioid receptor  kappa型阿片受体抗体

hz-3623R mu Opioid receptor  μ-型阿片受体抗体

hz-3724R Phospho-mu Opioid Receptor (Ser375)  磷酸化μ-型阿片受体抗体

hz-3624R Delta Opioid Receptor  D型阿片受体抗体

hz-3712R Phospho-delta Opioid Receptor (Ser363)  磷酸化D型阿片受体抗体

hz-3800R Kappa Light Chain  k轻链抗体

hz-1964R KLK3/Prostate Specific Antigen  激肽释放酶3/舒血管素3抗体

hz-1965R KLK4  激肽释放酶4抗体

hz-5869R KLK5  激肽释放酶5抗体

hz-5870R KLK6  激肽释放酶6抗体

hz-1966R KLK7  激肽释放酶7抗体

hz-5871R KLK8  激肽释放酶8抗体

hz-1967R KLK9  激肽释放酶9抗体（舒血管素9）

hz-2531R KLK10  激肽释放酶10抗体

hz-3799R KLK11  激肽释放酶11抗体

hz-5865R KLK12  激肽释放酶12抗体

hz-5866R KLK13  激肽释放酶13抗体

hz-1968R KLK14  激肽释放酶14抗体

hz-5867R KLK15  激肽释放酶15抗体

hz-3521R KMT6/EZH2  抑癌蛋白EZH2抗体

hz-1033R KRAS  原癌基因K-ras抗体

hz-3549R KSR1  Ras信号转导KSR1蛋白抗体

hz-3240R Phospho-KSR1 (Ser392)  磷酸化Ras信号转导KSR1蛋白抗体

hz-1357R Ku-70  DNA修复酶Ku70抗体

hz-1358R Ku-80  DNA修复酶Ku-80抗体

hz-4150R DRK1/Kv2.1  钾通道蛋白DRK1抗体

hz-5535R phospho-Kv2.1(Tyr128)  磷酸化钾通道蛋白DRK1抗体

hz-1575R Kv1.3/PCN3  离子通道蛋白Kv1.3抗体

hz-5402R KCNC1  离子通道蛋白Kv3.1抗体

hz-5403R phospho-KCNC1(Ser503)  磷酸化离子通道蛋白Kv3.1抗体