干扰素-β抗体（大鼠、小鼠）

干扰素-β抗体（大鼠、小鼠）产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

干扰素-β抗体（大鼠、小鼠）产品说明

       β型干扰素(Interferon-β,IFN-β)是主要由成纤维细胞产生的细胞因子,属于单一基因编码产生的蛋白质,可通过干扰病毒RNA或DNA复制而抑制病毒生长,并可显著增强NK细胞杀伤活性,通过促进MHCⅠ类分子表达而增强CTL对病毒感染细胞的识别和杀伤作用.
       The mammalian type I Inteferons (IFN1) are produced in response to viral infection and other inducers. They are divided into alpha and beta subtypes leukocytes and fibroblasts reactivity. The human IFN alphas are encoded by a family of at least 15 different genes, while IFN beta is the unique member of its subtype. There is approximately 50% amino acid homology between the alpha and beta subtypes. Both IFN subtypes are pleiotropic cytokines and have a similar range of biological activities. Differences between alpha subtypes, and between IFN alpha and betas, are in potency and cell type specific activities. In particular, IFN beta elicits a markedly higher antiproliferation response in some cell types such as, embryonal carcinoma, melanoma and melanocytes than do IFN alphas. Higher potency of IFN beta in treatment of multiple sclerosis and certain cancers has been observed. Type I IFNs signal through binding to a common cell surface receptor. Two chains of the receptor, IFNAR1 and IFNAR2, have been identified. Both chains are necessary for function and in the absence of either there is neither high affinity binding nor biological activity. The intracellular portions of the receptor subunits are bound by tyrosine kinases, Jak1 and Tyk2, members of the Janus kinase family. Upon ligand binding these kinases are activated and phosphorylate members of the STAT family of transcription factors, as well as IFNAR1 and 2. 
       Also known as: 
       Fibroblast interferon; IFB; IFF; IFN beta; IFNB 1; IFNB ; IFNB1; Interferon beta 1 fibroblast ; Interferon beta precursor; MGC96956

干扰素-β抗体（大鼠、小鼠）

hz-1207P GLUT3(Glucose transporter 3)  葡萄糖转运蛋白3抗原

hz-0999P GM-CSF(Granulocyte-Macrophage Colony Stimulating Factors)  粒细胞-巨噬细胞克隆刺激因子抗原

hz-1226P GPA33(glycoprotein A33 transmhzbrane)  糖蛋白A33(跨膜)抗原

hz-2426P glypican 1  磷脂酰基醇蛋白聚糖-1抗原

hz-1112P GPC3(glypican 3; Intestinal protein OCI-5; GTR2-2; MXR7)  磷脂酰基醇蛋白聚糖-3(多肽)

hz-2159P Glypican 4(Glypican proteoglycan 4)  磷脂酰基醇蛋白聚糖-4抗原

hz-1465P GRB2/ASH peptide  生长因子受体结合蛋白2抗原

hz-1351P GZMB/CCPI(Granzyme B)  颗粒酶B抗原

hz-1806P UTS2R/GPR14(Urotensin II receptor：G Protein Coupled Receptor 14)  G蛋白偶联受体14抗原

hz-1380P GPR30(G Protein Coupled Receptor 30)  G蛋白偶联受体30抗原

hz-1464P GnRHR peptide  促性腺激素释放激素受体抗原

hz-2501P KiSS-1R/GPR54/GPCR54(KiSS-1 receptor/G-Protein Coupled Receptor 54)  G蛋白偶联受体54抗原

hz-1209P GRK2/BARK1 (G-protein coupled receptor kinase 2)  G蛋白偶合受体激酶2抗原

hz-1161P GRM2/GLUR2 (Glutamate Receptor Metabotropic 2)  促代谢型谷氨酸受体2抗原

hz-0863P GRO Alpha/GRO/MGSA/CXCL1 protein (growthregulated oncogene Alpha)  生长调节致癌基因α/黑素瘤生长刺激因子α 抗原

hz-1219P GRP78(glucose regulated protein 78)  葡萄糖调节蛋白78抗原（热休克蛋白70蛋白5）

hz-2091P GSK-3 Alpha (Glycogen Synthase Kinase-3 alpha)  葡萄糖合成激酶-3α抗原(多肽抗原)

hz-2066P phospho-GSK-3 Beta(pSer9)  磷酸化葡萄糖合成激酶-3β抗原

hz-2073P phospho-GSK3 Alpha/ Beta(alpha + beta)(phospho Tyr279 + Tyr216)  磷酸化葡萄糖合成激酶3α/β抗原

hz-0837P GSR/GRase(glutathione reductase)  谷胱甘肽还原酶抗原

hz-1430P A/H1N1-M2 Human(Avian influenza Matrix Protein-2 Human)  A型人流感病毒H1N1-M2蛋白多肽

hz-0422P A/H1N1-M2 Swine(Avian influenza Matrix Protein-2 Swine)  A型猪流感病毒H1N1-M2蛋白

hz-2001P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-2002P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-2560P H2AX peptide  组蛋白H2AX多肽抗原

hz-2003P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-2004P H1N1(Influenza A virus ,hhzagglutinin)  流感病毒A抗原

hz-1235P Haase(hyaluronidase)  透明质酸酶/玻璃酸酶抗原

hz-0843P HA tag  HA tag标签多肽

hz-0966P HA tag(map)  HA tag标签（分支多肽）

hz-0540P HAI-1(Hepatocyte Growth Factor Activator Inhibitor 1)  肝细胞生长因子激活物抑制因子抗原

hz-0847P HBA1(hhzoglobin alpha 1)  人类血红蛋白α1抗原

hz-2169P VWCE/URG11(von Willebrand factor C and EGF domain-containing)  乙型肝炎病毒X蛋白(HBxAg)抗原