骨骼肌肌球蛋白轻链2抗体

英文名称    Fast skeletal Myosin    

中文名称    骨骼肌肌球蛋白轻链2抗体    

别    名    A1 catalytic; A2 catalytic; Alkali myosin light chain 1; Alkali myosin light chain 3; DKFZp779C0757; Fast skeletal myosin alkali light chain 1; Fast skeletal myosin light chain 2; MGC13450; MLC1F; MLC3F; MRLC 2; MRLC2; MYL 1; MYL1; MYL1 protein; MYLPF; Myosin light chain 1 alkali skeletal fast; Myosin light chain 1 skeletal muscle isoform; MLRS_HUMAN; Myosin light chain 2; Myosin light chain 3 skeletal muscle isoform; Myosin regulatory light chain 2.    

说 明 书    0.1ml  0.2ml      

研究领域    免疫学  信号转导  细胞骨架  细胞外基质      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 骨骼肌肌球蛋白轻链2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    19kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human MRLC2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

骨骼肌肌球蛋白轻链2抗体产品介绍    background:

Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins . Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.

Subunit:
Myosin is a hexamer of 2 heavy chains and 4 light chains.

Tissue Specificity:
Expressed in fetal and adult skeletal muscle.

Similarity:
Contains 3 EF-hand domains.    

骨骼肌肌球蛋白轻链2抗体

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