双甲基精氨酸水解酶1抗体

英文名称    DDAH1    

中文名称    双甲基精氨酸水解酶1抗体    

别    名    DDAH; DDAH I; DDAH-1; DDAH1; DDAH1_HUMAN; DDAHI; Dimethylargininase 1; Dimethylargininase-1; Dimethylarginine dimethylaminohydrolase 1; N(G); N(G)-dimethylarginine dimethylaminohydrolase 1; NG NG dimethylarginine dimethylaminohydrolase.    

说 明 书    0.2ml      

研究领域    心血管  细胞生物  神经生物学  血管内皮细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 双甲基精氨酸水解酶1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    31kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DDAH1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

双甲基精氨酸水解酶1抗体产品介绍    background:

DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).

Function:
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

Subunit:
Monomer.

Tissue Specificity:
Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.

Similarity:
Belongs to the DDAH family.

Database links:
UniProtKB/Swiss-Prot: O94760.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

双甲基精氨酸水解酶1抗体

hz-0805P CD56/NCAM1(Neural Cell Adhesion Molecule 1)  神经细胞粘附分子1抗原

hz-1036P CD62L (ELAM-1/L-Selectin )  L选择素抗原

hz-1273P E-Selectin  E选择素抗原

hz-1479P CD80/B7-1(human)  人刺激分子B7-1蛋白抗原

hz-2211P CD80/B7-1  刺激分子B7-1蛋白抗原

hz-1470P CD82/KAI1 peptide  肿瘤转移抑制蛋白1抗原

hz-1035P CD86/B7-2  CD86抗原

hz-1341P Cdc2/P34CDC2/CDK1(Cell division control protein 2)  周期素依赖激酶1抗原

hz-1448P CD339/Jagged1  CD339/Jagged1抗原

hz-1392P Cdc34 peptide  细胞周期调控因子34抗原

hz-0542P CDK1 (Cyclin-Dependent Kinase 1)  周期素依赖性激酶1抗原

hz-2076PB METH/BSA (Methamphetamine/BSA)  冰毒/甲基苯丙胺与牛血清蛋白偶联物

hz-0559P CDK5(Cyclin Dependent Kinase 5)  周期素依赖性激酶5抗原

hz-0568P CDK6 (Cyclin Dependent Kinase 6)  周期素依赖性激酶6抗原

hz-0569P CDK7/Cyclin H/MAT1  周期素依赖性激酶7抗原

hz-0570P CDK8(Cyclin Dependent Kinase 8)  周期素依赖性激酶8抗原

hz-0538P Cdkn1c/p57/Kip2 (Cyclindependent kinase inhibitor 1C)  周期蛋白依赖激酶抑制因子1C抗原

hz-1093P CGP-39/YKL-40(Chitinase-3-like protein 1 )  软骨糖蛋白39（多肽）

hz-0719P CEA(Carcinohzbryonic Antigen )peptide  人癌胚抗原抗原

hz-2080P Cecropin  抗菌肽/天蚕素（多肽）

hz-2048P HER2 receptor(erbB-2 isoform 2)  c-erbB-2受体抗原

hz-1454P ErbB-3/HER3(Epidermal growth factor receptor3)  表皮生长因子受体3(抗原)

hz-1085P C-erbB-4/HER4/erbB-4 (epidermal growth factor receptor4)  c-erbB-4癌基因抗原

hz-1277P CFTR(cystic fibrosis transmhzbrane conductance regulator)  囊性纤维化跨膜转运调节因子抗原

hz-0775P CG6856-PA peptide  CG6856-PA抗原

hz-0539P CGA(Chromogranin A)  嗜铬粒素A抗原

hz-0543P CGB(Chromogranin B)  嗜铬粒素B抗原

hz-1150P ChRM1(muscarinic acetylcholine receptor)  毒蕈碱型乙酰胆碱受体M1抗原

hz-1289P ChRM3 peptide  毒蕈碱型乙酰胆碱受体M3抗原

hz-1059P CK18(Cytokeratin 18)  细胞角蛋白18(多肽)

hz-2043P CK18 peptide  细胞角蛋白18多肽抗原

hz-1339P CK18(Cytokeratin 18)  细胞角蛋白18抗原（C端）