英文名称 DDAH1
中文名称 双甲基精氨酸水解酶1抗体
别 名 DDAH; DDAH I; DDAH-1; DDAH1; DDAH1_HUMAN; DDAHI; Dimethylargininase 1; Dimethylargininase-1; Dimethylarginine dimethylaminohydrolase 1; N(G); N(G)-dimethylarginine dimethylaminohydrolase 1; NG NG dimethylarginine dimethylaminohydrolase.
说 明 书 0.2ml
研究领域 心血管 细胞生物 神经生物学 血管内皮细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 双甲基精氨酸水解酶1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDAH1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
双甲基精氨酸水解酶1抗体产品介绍 background:
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
Function:
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
Subunit:
Monomer.
Tissue Specificity:
Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.
Similarity:
Belongs to the DDAH family.
Database links:
UniProtKB/Swiss-Prot: O94760.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双甲基精氨酸水解酶1抗体
hz-0805P CD56/NCAM1(Neural Cell Adhesion Molecule 1) 神经细胞粘附分子1抗原
hz-1036P CD62L (ELAM-1/L-Selectin ) L选择素抗原
hz-1273P E-Selectin E选择素抗原
hz-1479P CD80/B7-1(human) 人刺激分子B7-1蛋白抗原
hz-2211P CD80/B7-1 刺激分子B7-1蛋白抗原
hz-1470P CD82/KAI1 peptide 肿瘤转移抑制蛋白1抗原
hz-1035P CD86/B7-2 CD86抗原
hz-1341P Cdc2/P34CDC2/CDK1(Cell division control protein 2) 周期素依赖激酶1抗原
hz-1448P CD339/Jagged1 CD339/Jagged1抗原
hz-1392P Cdc34 peptide 细胞周期调控因子34抗原
hz-0542P CDK1 (Cyclin-Dependent Kinase 1) 周期素依赖性激酶1抗原
hz-2076PB METH/BSA (Methamphetamine/BSA) 冰毒/甲基苯丙胺与牛血清蛋白偶联物
hz-0559P CDK5(Cyclin Dependent Kinase 5) 周期素依赖性激酶5抗原
hz-0568P CDK6 (Cyclin Dependent Kinase 6) 周期素依赖性激酶6抗原
hz-0569P CDK7/Cyclin H/MAT1 周期素依赖性激酶7抗原
hz-0570P CDK8(Cyclin Dependent Kinase 8) 周期素依赖性激酶8抗原
hz-0538P Cdkn1c/p57/Kip2 (Cyclindependent kinase inhibitor 1C) 周期蛋白依赖激酶抑制因子1C抗原
hz-1093P CGP-39/YKL-40(Chitinase-3-like protein 1 ) 软骨糖蛋白39(多肽)
hz-0719P CEA(Carcinohzbryonic Antigen )peptide 人癌胚抗原抗原
hz-2080P Cecropin 抗菌肽/天蚕素(多肽)
hz-2048P HER2 receptor(erbB-2 isoform 2) c-erbB-2受体抗原
hz-1454P ErbB-3/HER3(Epidermal growth factor receptor3) 表皮生长因子受体3(抗原)
hz-1085P C-erbB-4/HER4/erbB-4 (epidermal growth factor receptor4) c-erbB-4癌基因抗原
hz-1277P CFTR(cystic fibrosis transmhzbrane conductance regulator) 囊性纤维化跨膜转运调节因子抗原
hz-0775P CG6856-PA peptide CG6856-PA抗原
hz-0539P CGA(Chromogranin A) 嗜铬粒素A抗原
hz-0543P CGB(Chromogranin B) 嗜铬粒素B抗原
hz-1150P ChRM1(muscarinic acetylcholine receptor) 毒蕈碱型乙酰胆碱受体M1抗原
hz-1289P ChRM3 peptide 毒蕈碱型乙酰胆碱受体M3抗原
hz-1059P CK18(Cytokeratin 18) 细胞角蛋白18(多肽)
hz-2043P CK18 peptide 细胞角蛋白18多肽抗原
hz-1339P CK18(Cytokeratin 18) 细胞角蛋白18抗原(C端)
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