英文名称 DDRGK1
中文名称 DDRGK1蛋白抗体
别 名 Chromosome 20 open reading frame 116; DDRGK domain containing 1; DDRGK domain containing protein 1; DDRGK domain-containing protein 1; DDRGK_HUMAN; Ddrgk1; MGC2592; RGD1309979; RP23-100C5.9; dJ1187M17.3; 1110001I20Rik; 2600009E05Rik; C20orf116.
说 明 书 0.2ml
研究领域 细胞生物 免疫学 神经生物学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 DDRGK1蛋白抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDRGK1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DDRGK1蛋白抗体产品介绍 background:
DDRGK1 (DDRGK domain-containing protein 1), also known as C20orf116, is a 314 amino acid secreted protein. DDRGK1 contains one PCI domain and is expressed as two isoforms produced by alternative splicing. The gene that encodes DDRGK1 maps to human chromosome 20, which represents about 2% of human DNA and consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought to be important for seminal production. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20.
Subcellular Location:
Endoplasmic reticulum.
Tissue Specificity:
Ubiquitously expressed (at protein level).
Post-translational modifications:
Ufmylated. Conjugated to ubiquitin-like protein UFM1, probably at Lys-267. The role of ufmylation is unclear.
Similarity:
Belongs to the DDRGK1 family.
Contains 1 PCI domain.
Database links:
UniProtKB/Swiss-Prot: Q96HY6.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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