细胞因子受体样因子1抗体

英文名称    CRLF1    

中文名称    细胞因子受体样因子1抗体    

别    名    CISS 1; CISS; CISS1; CLF 1; CLF; CLF1; CRLF 1; Cytokine like factor 1; Cytokine receptor like factor 1; cytokine receptor-like factor 1; NR 6; NR6; ZcytoR 5; ZcytoR5; CRLF1_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  细胞膜受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 细胞因子受体样因子1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    43kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CRLF1 (201-300aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞因子受体样因子1抗体产品介绍    background:

CRLF1 is a 422 amino acid secreted protein that interacts with cells expressing ciliary neurotrophic factor receptors. A cytokine receptor subunit belonging to the type I cytokine receptor family and type 3 subfamily, CRLF1 is thought to play a role in fetal nervous system development and immunity. CRLF1 is highly expressed in stomach, placenta, heart, ovary, thyroid, bone marrow, appendix, lymph node, spleen, thymus and fetal lung, and promotes neuronal cell survival. CRLF3 is a 442 amino acid protein that contains one fibronectin type-III domain. CRLF3 is expressed in lesion actinic keratosis (AK) and skin and squamous cell carcinoma (SCC), and is thought to negatively regulate the G0/G1 phase of the cell cycle.

Function:
CRLF1 (Cytokine receptor-like factor 1) is a cytokine receptor subunit. It forms a heteromeric complex with cardiotrophin-like cytokine (CLC) and the CRLF1/CLC complex is a ligand for the ciliary neurotrophic factor receptor (CNTFR). Mutations in CRLF1 are responsible for both Crisponi and cold-induced sweating syndromes.    

细胞因子受体样因子1抗体

hz-2664R MRC1/CD206  巨噬细胞甘露糖受体抗体

hz-5043R CLPS  胰辅脂酶抗体

hz-0668R C-Met/Met/HGFR  肝细胞生长因子受体抗体

hz-5754R SP17/CT22  精子表面蛋白Sp17抗体

hz-3271R Phospho-Met (Tyr1003)  磷酸化肝细胞生长因子受体(原癌基因)抗体

hz-3272R Phospho-Met(Tyr1234/1235)  磷酸化肝细胞生长因子受体(原癌基因)抗体

hz-3273R Phospho-Met(Tyr1349)  磷酸化肝细胞生长因子受体(原癌基因)抗体

hz-2530R CMKLR1  趋化样因子受体1抗体

hz-5755R Nucleoprotein TPR  核蛋白易位启动子区域TPR抗体

hz-5756R VAM1/MPP6  棕榈酰化膜蛋白6抗体

hz-0334R MTLC  致癌基因抗体

hz-1732R phospho C-Myc(Thr58/pSer62)  磷酸化致癌基因C-Myc抗体

hz-1733R phospho C-Met/HGFR(Tyr1365)  磷酸化原癌基因c-Met抗体

hz-0842R c-Myc tag  c-Myc tag标签抗体

hz-2113R AU5 tag  AU5 tag标签抗体

hz-2114R AU1 tag  AU1 tag标签抗体

hz-2115R Glu-Glu Tag  Glu-Glu tag抗体

hz-2116R E Tag  E Tag标签抗体

hz-2074R CNGA2  环核苷酸阳离子通道蛋白α2抗体

hz-1693R CANX/Calnexin  钙连蛋白抗体

hz-5757R FAM13B1  FAM13B1蛋白抗体

hz-1000R CNP/CNPase  C型钠尿肽抗体

hz-1683R CNR1/CB1  钙粘蛋白相关的神经受体1抗体

hz-2377R CNR2/CB2  钙粘蛋白相关的神经受体2抗体

hz-1516R CNTFR-α  睫状神经营养因子受体α抗体

hz-1711R CNR-2/PCDHA6  钙粘蛋白相关的神经受体2抗体

hz-1272R CNTF  睫状神经营养因子抗体

hz-3099R Phospho-Cofilin(Ser3)  磷酸化丝切蛋白抗体

hz-5258R Phospho-Cofilin/CFL1 (Tyr139)  磷酸化丝切蛋白抗体

hz-5259R phospho-CFL1/CFL2 (Tyr88)  磷酸化丝切蛋白抗体

hz-2541R COLEC12  凝集胎盘蛋白1抗体

hz-0578R Collagen I  Ⅰ型胶原抗体

hz-0709R Collagen II/Chondrocalcin  Ⅱ型胶原α1蛋白/软骨钙素抗体

hz-5758R FAP/FAPA  成纤维细胞激活蛋白α抗体

hz-5760R FAP1/PTPN13  Fas相关磷酸酶1/蛋白酪氨酸磷酸酶非受体型13抗体