钙离子通道a1F亚型抗体

英文名称    CACNA1F    

中文名称    钙离子通道a1F亚型抗体    

别    名    CACNA 1F; CACNAF; CACNAF1; Calcium channel voltage dependent alpha 1F subunit; Calcium channel voltage dependent L type alpha 1F subunit; Cav1.4; Cav1.4alpha1; COD 3; COD3; CORDX 3; CORDX; CORDX3; CSNB2A; CSNBX 2; CSNBX2; JM 8; JM8; JMC 8; JMC8; Voltage ated calcium channel subunit alpha Cav1.4; Voltage ependent L ype calcium channel subunit alpha F; CAC1F_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    神经生物学  信号转导  通道蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 钙离子通道a1F亚型抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    221kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CACNA1F    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

钙离子通道a1F亚型抗体产品介绍    background:

Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression.Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. L-type Ca2+ currents initiate muscle contraction, endocrine secretion, and gene transcription, and can be regulated through second-messenger activated protein phosphorylation pathways. L-type calcium channels may form macromolecular signaling complexes with G protein-coupled receptors, thereby enhancing the selectivity of regulating specific targets.

Function:
CACNA1F (Calcium channel, voltage-dependent, L type, alpha 1F subunit) is a subunit of a voltage-dependent calcium channel complex. Voltage-gated calcium channels mediate the entry of calcium ions into excitable cells. CACNA1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the "high-voltage activated" (HVA) group and are blocked by dihydropyridines (DHP).    

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