英文名称 Calponin 1 + 2 + 3
中文名称 钙结合蛋白Calponin抗体
别 名 smooth muscle; Basic calponin; Calponin 1; Calponin 2; Calponin 3; Calponin1; Calponin2; Calponin3; Calponin-1; Calponin-2; Calponin-3; Calponin 1 basic smooth muscle; Calponin H1; Calponin H1 smooth muscle; Calponins basic; CNN 1; Cnn1; CNN2_HUMAN; Sm Calp; SMCC.
说 明 书 0.2ml
研究领域 心血管 细胞生物 信号转导 干细胞 结合蛋白 细胞类型标志物 细胞骨架
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 IEM=1:20-200 IGS=1:20-200 GICA=1:20-200 钙结合蛋白Calponin抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Calponin 1/2/3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
钙结合蛋白Calponin抗体产品介绍 background:
Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.
Function:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
钙结合蛋白Calponin抗体
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hz-2560R Histone H2A.x 组蛋白H2AX抗体
hz-3185R Phospho-Histone H2A.X (Ser139) 磷酸化组蛋白H2AX抗体
hz-5360R Phospho-Histone H2A.X (Tyr143) 磷酸化组蛋白H2AX抗体
hz-3652R Histone H2B 组蛋白H2B抗体
hz-3782R Acetyl-Histone H2B(K5) 乙酰化组蛋白H2B抗体
hz-3783R Acetyl-Histone H2B(K20) 乙酰化组蛋白H2B抗体
hz-2003R H1N1 Hhzagglutinin 2 甲型流感病毒血凝素抗体
hz-2004R H1N1 Hhzagglutinin 2 甲型流感病毒血凝素抗体
hz-4619R H1N1/H5N1/H3N2 nucleocapsid protein A型流感病毒核衣壳蛋白抗体
hz-4620R H1N1/H5N1/H3N2 nucleocapsid protein A型流感病毒核衣壳蛋白抗体
hz-4621R H1N1/H5N1/H3N2 nucleocapsid protein A型流感病毒核衣壳蛋白抗体
hz-5888R Hyaluronidase2 透明质酸酶2/玻璃酸酶2抗体
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hz-3837R Hamartin/TSC1 结节性硬化症蛋白1抗体
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hz-3661R SCHAD/HADHSC(mouse, rat) 短链L-3羟烷基辅酶A脱氢酶抗体(小鼠,大鼠)
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