CD101抗体

英文名称    CD101    

中文名称    CD101抗体    

别    名    IGSF2; Immunoglobulin superfamily member 2; Leukocyte surface protein; V7; V7 LSB; IGSF2_HUMAN; IgSF2; Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD101.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  t-淋巴细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200CD101抗体 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    113kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human IGSF1/CD101    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

CD101抗体产品介绍    background:

CD101 is a disulfide-linked homodimeric type 1 glycoprotein. The peptide is comprised of 7 extracellular V-type IgSF domains. CD101 is highly expressed on monocytes, granulocytes, mucosal T cells, and on activated peripheral blood T cells. Expression is weak on resting T and B and NK cells, absent from platelets and weak or absent from most hematopoietic cell lines. CD101 is thought to play a co-stimulatory role in TCR/CD3-mediated T cell activation. Monoclonal antibodies against CD101 inhibit allogeneic T cell responses. Studies suggest that CD101 plays a major role in the activation of T cells by skin dendritic cells. 

Function:
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.    

CD101抗体

hz-8093R CCDC60  卷曲螺旋结构域蛋白60抗体

hz-8094R CCDC89  卷曲螺旋结构域蛋白89抗体

hz-8095R CCDC114  卷曲螺旋结构域蛋白114抗体

hz-4030R Pancreatic Amylase  胰淀粉酶抗体

hz-8096R CCDC39  卷曲螺旋结构域蛋白39抗体

hz-8097R CCDC30  卷曲螺旋结构域蛋白30抗体

hz-8098R CCDC34  卷曲螺旋结构域蛋白34抗体

hz-8099R CCDC75  卷曲螺旋结构域蛋白75抗体

hz-8100R CCDC65  卷曲螺旋结构域蛋白65抗体

hz-2381R Signal recognition particle  信号识别颗粒抗体

hz-8101R CCDC157  卷曲螺旋结构域蛋白157抗体

hz-8102R CCDC90B  卷曲螺旋结构域蛋白90B抗体

hz-8103R CCDC104  卷曲螺旋结构域蛋白104抗体

hz-8104R CCDC12  卷曲螺旋结构域蛋白12抗体

hz-8105R CCDC67  卷曲螺旋结构域蛋白67抗体

hz-8106R CCDC144A  卷曲螺旋结构域蛋白144A抗体

hz-8107R CCDC129  卷曲螺旋结构域蛋白129抗体

hz-8108R CCDC107  卷曲螺旋结构域蛋白107抗体

hz-8111R CCDC116  卷曲螺旋结构域蛋白116抗体

hz-8112R CCDC117  卷曲螺旋结构域蛋白117抗体

hz-8113R CCDC127  卷曲螺旋结构域蛋白127抗体

hz-8114R CCDC138  卷曲螺旋结构域蛋白138抗体

hz-8115R CCDC144NL  卷曲螺旋结构域蛋白144NL抗体

hz-8116R CCDC56  卷曲螺旋结构域蛋白56抗体

hz-8117R CCDC146  卷曲螺旋结构域蛋白146抗体

hz-8118R CCDC147  卷曲螺旋结构域蛋白147抗体

hz-0800R ANGPTL1/Angiopoietin 1/ANG-1  血管生成素-1抗体

hz-8119R CCDC148  卷曲螺旋结构域蛋白148抗体

hz-0677R Angiopoietin 2/ANG2  血管生成素2抗体

hz-8121R CCDC153  卷曲螺旋结构域蛋白153抗体

hz-8122R CCDC158  卷曲螺旋结构域蛋白158抗体

hz-8123R CCDC160  卷曲螺旋结构域蛋白160抗体

hz-8124R CCDC22  卷曲螺旋结构域蛋白22抗体

hz-8125R CCDC25  卷曲螺旋结构域蛋白25抗体