转铁蛋白受体抗体

英文名称    Transferrin receptor    

中文名称    转铁蛋白受体抗体    

别    名    CD 71; CD71; CD71 antigen; p90; T9; TFR 1; TFR; TFR1; TFRC; TR; Transferrin receptor (p90 CD71); Transferrin Receptor Protein 1; OTTHUMP00000208523; OTTHUMP00000208524; OTTHUMP00000208525; Transferrin receptor protein 1, serum form; TRFR.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  心血管  细胞生物  免疫学  信号转导  干细胞  转录调节因子  细胞表面分子  细胞类型标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 IF=1:50-200 转铁蛋白受体抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    74/85kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Transferrin receptor    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

转铁蛋白受体抗体产品介绍    background:

Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C terminal binding site. The antigen is present on most dividing cells, including normally cycling in vivo hematopoietic progenitor cells, mitogenically stimulated cells in vitro, some primary tumor cells and most proliferating cells in vitro.

Function:
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.    

转铁蛋白受体抗体

hz-6904R PRC1  胞质分裂调控蛋白1抗体

hz-6905R CDCREL/SEPT5  细胞周期调控相关蛋白1

hz-6906R SEPT6  细胞分化蛋白SEPT6抗体

hz-6907R Septin 8  细胞分化蛋白SEPT8抗体

hz-6908R CCDC5  卷曲螺旋结构域蛋白5抗体

hz-6909R BMP9  骨形态发生蛋白9抗体

hz-6910R BMPER  BMP内皮细胞调节蛋白抗体

hz-2132R Angiotensin II type 1A receptor  血管紧张素Ⅱ1A型受体抗体

hz-6911R Entactin/Nidogen  巢蛋白1抗体

hz-6912R Cyclin M2/CNNM2  周期素M2抗体

hz-6913R FRS2  成纤维细胞生长因子受体底物2抗体

hz-6914R FER/TYK3  酪氨酸蛋白激酶3抗体

hz-6915R AUTS2  孤独症易感基因2蛋白抗体（自闭症相关蛋白1）

hz-6916R RABX5/Rabex5  G蛋白相关RABX5抗体

hz-6918R PPAPDC3  磷脂酸磷酸酶2结构域3抗体

hz-6919R CCDC69  卷曲螺旋结构域蛋白69抗体

hz-6920R CCDC50  卷曲螺旋结构域蛋白50抗体

hz-6921R CCDC98  卷曲螺旋结构域蛋白98抗体

hz-6922R CCDC47  卷曲螺旋结构域蛋白47抗体

hz-6923R CCDC70  卷曲螺旋结构域蛋白70抗体

hz-6924R CCDC90A  卷曲螺旋结构域蛋白90A抗体

hz-6925R CCDC51  卷曲螺旋结构域蛋白51抗体

hz-6926R CCDC125  卷曲螺旋结构域蛋白125抗体

hz-6927R CCDC37  卷曲螺旋结构域蛋白37抗体

hz-6928R CCDC17  卷曲螺旋结构域蛋白17抗体

hz-6929R DCTN1/Dynactin 1  动力蛋白激活蛋白1抗体

hz-6930R SNF1LK2/SIK2  丝氨酸/苏氨酸蛋白激酶SIK2抗体

hz-6932R SHARP1/DEC2  转录调节因子DEC2抗体

hz-6933R MICB  MHC I类链相关蛋白B

hz-6934R TAPA1/CD81  CD81抗体

hz-6935R HAND2  心脏和神经嵴衍生蛋白2抗体

hz-6936R MYF5  生肌决定因子Myf5抗体

hz-6937R SCC112/PIG54  细胞增殖诱导蛋白54抗体

hz-6938R EBNA1/EBV Nuclear Antigen  EB病毒核抗原1抗体