过敏毒素C3受体/补体C3受体抗体

英文名称    C3a Receptor    

中文名称    过敏毒素C3受体/补体C3受体抗体    

别    名    AZ 3B; AZ3B; C3a anaphylatoxin chemotactic receptor; C3A R; C3A R1; C3a-R; C3AR; C3AR_HUMAN; C3AR1; C3R1; Complement component 3 receptor 1; Complement component 3a receptor 1; HNFAG09.    

说 明 书    0.1ml  0.2ml      

研究领域    免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 过敏毒素C3受体/补体C3受体抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    54kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human C3a Receptor/C3aR    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

过敏毒素C3受体/补体C3受体抗体产品介绍    background:

Complement C3 precursor contains complement C3 beta chain, complement C3 alpha chain, C3a anaphylatoxin, complement C3b alpha chain, complement C3c fragment, complement C3dg fragment, complement C3g fragment, complement C3d fragment and complement C3f fragment. C3a, C4a, and C5a are potent anaphylatoxins that are released during complement activation, a system of ligand-surface protein interactions specific to cells of hematopoietic lineage that aids in the elimination of pathogens. C3a and C5a secretion correlates with pathophysiological phenotypes such as asthma and bacterial meningitis. Binding of these proteins to their respective G protein-coupled receptors (C3aR, C5aR), which are present on the surface of myeloid leukocytes, induces proinflammatory events such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3aR is expressed in brain and activated B-lymphocytes whereas C5aR is prevalent on the surface of hepatocyte, lung, smooth muscle, and endothelial cells. Upon activation, C3aR and C5aR are susceptible to rapid GRK-mediated phosphorylation and clathrin-coated vesicle targeting. C5aR utilizes the Ras-Raf-ERK1/2 cascade and couples to Gi/G16 proteins.

Function:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.    

过敏毒素C3受体/补体C3受体抗体

hz-9750R ANKRD45/CT117  肿瘤/睾丸抗原117

hz-9751R ANKRD50  锚蛋白重复结构域蛋白50抗体

hz-9753R ATP6V1G2/V-ATPase G2  氢离子转运ATP合成酶6G抗体

hz-9754R ATXN7L3B  共济失调7样蛋白3B抗体

hz-9755R ANKRD26  锚蛋白重复结构域蛋白26抗体

hz-9756R ANKRD26  锚蛋白重复结构域蛋白26抗体

hz-9757R BAT5  白细胞抗原B相关转录蛋白5抗体

hz-9758R Ephrin A2/LERK6  Ephrin A2抗体

hz-9759R Brd4/CAP  染色体相关蛋白CAP抗体

hz-9760R FGF12  成纤维细胞生长因子12抗体

hz-9761R FGF14  成纤维细胞生长因子14抗体

hz-9762R FGF18  成纤维细胞生长因子18抗体

hz-9763R BCL7C  B细胞白血病/淋巴瘤蛋白7抗体

hz-9764R phospho-Stathmin 1 (Ser63)  磷酸化原癌基因蛋白18抗体

hz-9765R phospho-Stathmin 1 (Ser24)  磷酸化原癌基因蛋白18抗体

hz-9766R INTS3  集成复杂蛋白亚单位3抗体

hz-9767R C10orf4/FRA10AC1  10号染色体开放阅读框4抗体

hz-9768R C10orf47  10号染色体开放阅读框47抗体

hz-9769R C10orf62  10号染色体开放阅读框62抗体

hz-9770R C10orf81  10号染色体开放阅读框81抗体

hz-9771R C10orf88  10号染色体开放阅读框88抗体

hz-9772R C10orf93  10号染色体开放阅读框93抗体

hz-9773R C10orf63/Enkurin  10号染色体开放阅读框63抗体

hz-9774R C10orf132/GOLGA7B  10号染色体开放阅读框132抗体

hz-9775R C10orf30/BEND7  10号染色体开放阅读框30抗体

hz-9776R C10orf140  10号染色体开放阅读框140抗体

hz-9777R C1orf125  1号染色体开放阅读框125抗体

hz-9778R C1orf129  1号染色体开放阅读框129抗体

hz-9779R C1orf159  1号染色体开放阅读框159抗体

hz-9780R C1orf163  1号染色体开放阅读框163抗体

hz-9781R C1orf172  1号染色体开放阅读框172抗体

hz-9782R C1orf2/COTE1  1号染色体开放阅读框2抗体

hz-9783R C1orf19/SEN15  1号染色体开放阅读框19抗体

hz-9784R C1orf25  1号染色体开放阅读框25抗体

hz-9785R C1orf31  1号染色体开放阅读框31抗体

hz-9786R C1orf51  1号染色体开放阅读框51抗体

hz-9787R C1orf52  1号染色体开放阅读框52抗体

hz-9788R C1orf67/DNAH14  1号染色体开放阅读框67抗体

hz-9789R C1orf83  1号染色体开放阅读框83抗体

hz-9790R AFAP/AFAP-110  微丝相关蛋白1抗体

hz-9791R C1ORF111  1号染色体开放阅读框111抗体

hz-9792R C1ORF74  1号染色体开放阅读框74抗体

hz-9793R C1QL2/C1QTNF10  补体C1q和肿瘤坏死因子相关蛋白10

hz-9794R C1orf93  1号染色体开放阅读框93抗体