英文名称 C3a Receptor
中文名称 过敏毒素C3受体/补体C3受体抗体
别 名 AZ 3B; AZ3B; C3a anaphylatoxin chemotactic receptor; C3A R; C3A R1; C3a-R; C3AR; C3AR_HUMAN; C3AR1; C3R1; Complement component 3 receptor 1; Complement component 3a receptor 1; HNFAG09.
说 明 书 0.1ml 0.2ml
研究领域 免疫学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 过敏毒素C3受体/补体C3受体抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C3a Receptor/C3aR
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
过敏毒素C3受体/补体C3受体抗体产品介绍 background:
Complement C3 precursor contains complement C3 beta chain, complement C3 alpha chain, C3a anaphylatoxin, complement C3b alpha chain, complement C3c fragment, complement C3dg fragment, complement C3g fragment, complement C3d fragment and complement C3f fragment. C3a, C4a, and C5a are potent anaphylatoxins that are released during complement activation, a system of ligand-surface protein interactions specific to cells of hematopoietic lineage that aids in the elimination of pathogens. C3a and C5a secretion correlates with pathophysiological phenotypes such as asthma and bacterial meningitis. Binding of these proteins to their respective G protein-coupled receptors (C3aR, C5aR), which are present on the surface of myeloid leukocytes, induces proinflammatory events such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3aR is expressed in brain and activated B-lymphocytes whereas C5aR is prevalent on the surface of hepatocyte, lung, smooth muscle, and endothelial cells. Upon activation, C3aR and C5aR are susceptible to rapid GRK-mediated phosphorylation and clathrin-coated vesicle targeting. C5aR utilizes the Ras-Raf-ERK1/2 cascade and couples to Gi/G16 proteins.
Function:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
过敏毒素C3受体/补体C3受体抗体
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hz-9755R ANKRD26 锚蛋白重复结构域蛋白26抗体
hz-9756R ANKRD26 锚蛋白重复结构域蛋白26抗体
hz-9757R BAT5 白细胞抗原B相关转录蛋白5抗体
hz-9758R Ephrin A2/LERK6 Ephrin A2抗体
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hz-9760R FGF12 成纤维细胞生长因子12抗体
hz-9761R FGF14 成纤维细胞生长因子14抗体
hz-9762R FGF18 成纤维细胞生长因子18抗体
hz-9763R BCL7C B细胞白血病/淋巴瘤蛋白7抗体
hz-9764R phospho-Stathmin 1 (Ser63) 磷酸化原癌基因蛋白18抗体
hz-9765R phospho-Stathmin 1 (Ser24) 磷酸化原癌基因蛋白18抗体
hz-9766R INTS3 集成复杂蛋白亚单位3抗体
hz-9767R C10orf4/FRA10AC1 10号染色体开放阅读框4抗体
hz-9768R C10orf47 10号染色体开放阅读框47抗体
hz-9769R C10orf62 10号染色体开放阅读框62抗体
hz-9770R C10orf81 10号染色体开放阅读框81抗体
hz-9771R C10orf88 10号染色体开放阅读框88抗体
hz-9772R C10orf93 10号染色体开放阅读框93抗体
hz-9773R C10orf63/Enkurin 10号染色体开放阅读框63抗体
hz-9774R C10orf132/GOLGA7B 10号染色体开放阅读框132抗体
hz-9775R C10orf30/BEND7 10号染色体开放阅读框30抗体
hz-9776R C10orf140 10号染色体开放阅读框140抗体
hz-9777R C1orf125 1号染色体开放阅读框125抗体
hz-9778R C1orf129 1号染色体开放阅读框129抗体
hz-9779R C1orf159 1号染色体开放阅读框159抗体
hz-9780R C1orf163 1号染色体开放阅读框163抗体
hz-9781R C1orf172 1号染色体开放阅读框172抗体
hz-9782R C1orf2/COTE1 1号染色体开放阅读框2抗体
hz-9783R C1orf19/SEN15 1号染色体开放阅读框19抗体
hz-9784R C1orf25 1号染色体开放阅读框25抗体
hz-9785R C1orf31 1号染色体开放阅读框31抗体
hz-9786R C1orf51 1号染色体开放阅读框51抗体
hz-9787R C1orf52 1号染色体开放阅读框52抗体
hz-9788R C1orf67/DNAH14 1号染色体开放阅读框67抗体
hz-9789R C1orf83 1号染色体开放阅读框83抗体
hz-9790R AFAP/AFAP-110 微丝相关蛋白1抗体
hz-9791R C1ORF111 1号染色体开放阅读框111抗体
hz-9792R C1ORF74 1号染色体开放阅读框74抗体
hz-9793R C1QL2/C1QTNF10 补体C1q和肿瘤坏死因子相关蛋白10
hz-9794R C1orf93 1号染色体开放阅读框93抗体
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