钙调蛋白激酶CaMK1D抗体

英文名称    CAMK1D    

中文名称    钙调蛋白激酶CaMK1D抗体    

别    名    Calcium/calmodulin dependent protein kinase ID; Calcium/calmodulin dependent protein kinase type 1D; CaM K1; CaM KI delta; CaM kinase I delta; CaM kinase ID; CAMK 1D; Camk1D; CaMKI delta; CamKI like protein kinase; CaMKID; CKLiK.    

说 明 书    0.2ml      

研究领域    肿瘤  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 钙调蛋白激酶CaMK1D抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    43kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CAMK1D    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

钙调蛋白激酶CaMK1D抗体产品介绍    background:

CAMK1D is a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. It may be involved in the regulation of granulocyte function through the chemokine signal transduction pathway and may play a role in apoptosis of erythroleukemia cells.

Function:
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.    

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