磷酸化细胞角蛋白18抗体

英文名称    phospho-CK18(Ser34)    

中文名称    磷酸化细胞角蛋白18抗体    

别    名    Cytokeratin 18 (phospho S34); p-Cytokeratin 18 (phospho S34); Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46; Cell proliferation-inducing gene 46 protein; CK 18; CK-18; CK18; CYK 18; CYK18; Cytokeratin 18; Cytokeratin endo B; Cytokeratin-18; Cytokeratin18; K 18; K18; K1C18_HUMAN; Keratin 18; Keratin D; Keratin type I cytoskeletal 18; keratin, type I cytoskeletal 18; Keratin-18; Keratin18; Kerd; KRT18.    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    肿瘤  信号转导  细胞类型标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Guinea Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化细胞角蛋白18抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    48kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human CK18 around the phosphorylation site of Ser34 [AA(p-S)VY]    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

磷酸化细胞角蛋白18抗体产品介绍    background:

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Function:
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.    

磷酸化细胞角蛋白18抗体

hz-1474R CCL28/MEC  粘膜相关上皮趋化因子28抗体

hz-1710R CCR10  细胞表面趋化因子受体10抗体

hz-1780R CCRK  细胞周期相关激酶抗体

hz-0527R CD10/CALLA/Neprilysin  CD10抗体

hz-0579R CD105/Endoglin  CD105抗体

hz-4262R cIAP1/RNF48  凋亡抑制因子1抗体

hz-4609R CD105/Endoglin  CD105抗体

hz-5803R API2  凋亡抑制因子2抗体

hz-5536R TRAK1  驱动蛋白结合蛋白1抗体

hz-0672R CD117/c-kit/SCFR  干细胞生长因子受体/细胞表面分化抗原抗体

hz-1738R phospho-c-kit(Tyr936)  磷酸化原癌基因c-kit抗体

hz-3241R Phospho-c-Kit(Tyr703)  磷酸化原癌基因c-kit抗体

hz-3242R Phospho-c-Kit(Tyr721)  磷酸化原癌基因c-kit抗体

hz-5400R Phospho-c-Kit(Ser741)  磷酸化原癌基因c-kit抗体

hz-0395R CD133 antigen  造血干细胞抗原CD133抗体

hz-5814R Prominin 2  造血干细胞抗原CD133相关蛋白抗体

hz-0209R CD133 antigen  造血干细胞抗原CD133抗体

hz-2449R CD137/TNFRSF9  肿瘤坏死因子受体超家族成员9抗体

hz-1309R CD138/Syndecan 1  多配体蛋白聚糖1抗体

hz-1618R CD146/MCAM  黑色素瘤细胞粘附分子CD146抗体

hz-5472R phospho-MCAM(Tyr641)  磷酸化黑色素瘤细胞粘附分子CD146抗体

hz-1783R CD141/THBD  凝血调节蛋白/血栓调节素抗体

hz-4132R Ron  原癌基因c-Met相关酪氨酸激酶抗体

hz-5489R phospho-MST1R(Ser1349)  磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-5490R phospho-MST1R(Tyr1238)  磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-4138R MAPK11/p38Beta  丝裂原活化的蛋白激酶p38β抗体

hz-5506R phospho-MAPK11(Thr180+Tyr182)  磷酸化丝裂原活化的蛋白激酶p38β抗体

hz-4141R NUDEL/NDEL1  中心粒蛋白Nudel抗体

hz-4212R Neuroligin 1  突触细胞粘附分子1抗体

hz-5522R phospho-NDEL1(Ser231)  磷酸化中心粒蛋白Nudel抗体

hz-5523R phospho-NDEL1(Ser242)  磷酸化中心粒蛋白Nudel抗体

hz-5524R phospho-NDEL1(Thr219)  磷酸化中心粒蛋白Nudel抗体

hz-1383R CD13/APN/ANPEN  CD13氨肽酶N抗体

hz-1192R CD14  内毒素受体抗体

hz-2491R CD27/TNFRSF7  CD27抗体

hz-1297R CD28  CD28抗体

hz-0878R CD144/VECD/VE Cadherin  上皮型钙粘附分子抗体

hz-4142R NPTX1  神经细胞正五聚体1抗体