英文名称 phospho-CK18(Ser34)
中文名称 磷酸化细胞角蛋白18抗体
别 名 Cytokeratin 18 (phospho S34); p-Cytokeratin 18 (phospho S34); Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46; Cell proliferation-inducing gene 46 protein; CK 18; CK-18; CK18; CYK 18; CYK18; Cytokeratin 18; Cytokeratin endo B; Cytokeratin-18; Cytokeratin18; K 18; K18; K1C18_HUMAN; Keratin 18; Keratin D; Keratin type I cytoskeletal 18; keratin, type I cytoskeletal 18; Keratin-18; Keratin18; Kerd; KRT18.
说 明 书 0.1ml
产品类型 磷酸化抗体
研究领域 肿瘤 信号转导 细胞类型标志物
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Guinea Pig,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化细胞角蛋白18抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CK18 around the phosphorylation site of Ser34 [AA(p-S)VY]
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
磷酸化细胞角蛋白18抗体产品介绍 background:
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Function:
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
磷酸化细胞角蛋白18抗体
hz-1474R CCL28/MEC 粘膜相关上皮趋化因子28抗体
hz-1710R CCR10 细胞表面趋化因子受体10抗体
hz-1780R CCRK 细胞周期相关激酶抗体
hz-0527R CD10/CALLA/Neprilysin CD10抗体
hz-0579R CD105/Endoglin CD105抗体
hz-4262R cIAP1/RNF48 凋亡抑制因子1抗体
hz-4609R CD105/Endoglin CD105抗体
hz-5803R API2 凋亡抑制因子2抗体
hz-5536R TRAK1 驱动蛋白结合蛋白1抗体
hz-0672R CD117/c-kit/SCFR 干细胞生长因子受体/细胞表面分化抗原抗体
hz-1738R phospho-c-kit(Tyr936) 磷酸化原癌基因c-kit抗体
hz-3241R Phospho-c-Kit(Tyr703) 磷酸化原癌基因c-kit抗体
hz-3242R Phospho-c-Kit(Tyr721) 磷酸化原癌基因c-kit抗体
hz-5400R Phospho-c-Kit(Ser741) 磷酸化原癌基因c-kit抗体
hz-0395R CD133 antigen 造血干细胞抗原CD133抗体
hz-5814R Prominin 2 造血干细胞抗原CD133相关蛋白抗体
hz-0209R CD133 antigen 造血干细胞抗原CD133抗体
hz-2449R CD137/TNFRSF9 肿瘤坏死因子受体超家族成员9抗体
hz-1309R CD138/Syndecan 1 多配体蛋白聚糖1抗体
hz-1618R CD146/MCAM 黑色素瘤细胞粘附分子CD146抗体
hz-5472R phospho-MCAM(Tyr641) 磷酸化黑色素瘤细胞粘附分子CD146抗体
hz-1783R CD141/THBD 凝血调节蛋白/血栓调节素抗体
hz-4132R Ron 原癌基因c-Met相关酪氨酸激酶抗体
hz-5489R phospho-MST1R(Ser1349) 磷酸化原癌基因c-Met相关酪氨酸激酶抗体
hz-5490R phospho-MST1R(Tyr1238) 磷酸化原癌基因c-Met相关酪氨酸激酶抗体
hz-4138R MAPK11/p38Beta 丝裂原活化的蛋白激酶p38β抗体
hz-5506R phospho-MAPK11(Thr180+Tyr182) 磷酸化丝裂原活化的蛋白激酶p38β抗体
hz-4141R NUDEL/NDEL1 中心粒蛋白Nudel抗体
hz-4212R Neuroligin 1 突触细胞粘附分子1抗体
hz-5522R phospho-NDEL1(Ser231) 磷酸化中心粒蛋白Nudel抗体
hz-5523R phospho-NDEL1(Ser242) 磷酸化中心粒蛋白Nudel抗体
hz-5524R phospho-NDEL1(Thr219) 磷酸化中心粒蛋白Nudel抗体
hz-1383R CD13/APN/ANPEN CD13氨肽酶N抗体
hz-1192R CD14 内毒素受体抗体
hz-2491R CD27/TNFRSF7 CD27抗体
hz-1297R CD28 CD28抗体
hz-0878R CD144/VECD/VE Cadherin 上皮型钙粘附分子抗体
hz-4142R NPTX1 神经细胞正五聚体1抗体
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