磷酸化细胞分裂周期蛋白6抗体

英文名称    phospho-Cdc6 (Ser54)    

中文名称    磷酸化细胞分裂周期蛋白6抗体    

别    名    Cell Division Cycle protein 6; Cdc 18L; Cdc 6; CDC18 (cell division cycle 18, S.pombe, homolog) like; CDC18 (S.pombe); CDC18 like; CDC18(S.pombe); Cdc18L; CDC6 related protein; Cdc6p; Cell cycle controller; Cell division control protein 6; Cell division control protein 6 homolog; Cell division cycle 18; Cell division cycle 18 homolog; Cell division cycle 6 homolog; Cell division cycle 6 protein; HsCDC 18; HsCDC 6; HsCDC18; HsCDC6; p62; p62(cdc 6); p62(cdc6); CDC6_HUMAN.    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    细胞生物  染色质和核信号  细胞周期蛋白  转录调节因子  细胞分化      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化细胞分裂周期蛋白6抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    63kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human Cdc6 around the phosphorylation site of Ser54 [PL(p-S)PR]    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化细胞分裂周期蛋白6抗体产品介绍    background:

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Function:
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.     

磷酸化细胞分裂周期蛋白6抗体

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