磷酸化细胞分裂周期蛋白25B抗体

英文名称    phospho-Cdc25B (Ser323)    

中文名称    磷酸化细胞分裂周期蛋白25B抗体    

别    名    Cdc25B (Phospho-Ser323); Cdc25B (Phospho-S323); p-Cdc25B (Ser323); p-Cdc25B (S323); Cdc 25B; Cdc25b; Cdc-25b; CDC25HU2; Cdc25m2; Cell division cycle 25 homolog B; Cell division cycle 25B; Cell division cycle 25B isoform 1; Cell division cycle 25B isoform 2; Cell division cycle 25B isoform 3; Cell division cycle 25B isoform 4; Cell division cycle 25B isoform 5; Dual specificity phosphatase Cdc25B; M phase inducer phosphatase 2; M-phase inducer phosphatase 2; MPIP2_HUMAN.    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    肿瘤  细胞生物  免疫学  细胞周期蛋白  激酶和磷酸酶  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化细胞分裂周期蛋白25B抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    65kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser323    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化细胞分裂周期蛋白25B抗体产品介绍    background:

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008].

Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.    

磷酸化细胞分裂周期蛋白25B抗体

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hz-11130R VAT1L/KIAA1576  突触小泡膜蛋白同源样蛋白1抗体

hz-1282R ASPP1  p53凋亡刺激蛋白1抗体

hz-11131R LALBA/alpha Lactalbumin  乳清蛋白α抗体

hz-11132R Lamin B2  核纤层蛋白B2抗体

hz-11133R PCDHAC2  原钙粘蛋白介导的PCDHαC2受体抗体

hz-11134R PCDHB15/PCDHB22  原钙粘蛋白15抗体

hz-11135R PCDHB16  原钙粘蛋白16抗体

hz-11136R PCDHB2  原钙粘蛋白β2抗体

hz-11138R PCDHB4  原钙粘蛋白β4抗体

hz-11139R PCDHB5  原钙粘蛋白β5抗体

hz-11140R PCDHB7  原钙粘蛋白β7抗体

hz-11141R PCDHGA1  原钙粘蛋白γA1抗体

hz-11143R PCDHGA10  原钙粘蛋白γ10抗体

hz-11144R PCDHGA4  原钙粘蛋白γA4抗体

hz-11145R PCDHGA2  原钙粘蛋白γA2抗体

hz-11146R PCDHGA3  原钙粘蛋白γA3抗体

hz-11147R PCDHGA5  原钙粘蛋白γA5抗体

hz-11148R PCDHGA7  原钙粘蛋白γA7抗体

hz-11149R PCDHGA8  原钙粘蛋白γA8抗体

hz-11150R PCDHGA9  原钙粘蛋白γA9抗体

hz-1283R ASPP2/p53BP2  P53凋亡刺激蛋白2抗体

hz-4240R DDIT4/REDD1  DNA损伤诱导转录蛋白4抗体

hz-11151R PCDHGA11  原钙粘蛋白γA11抗体

hz-11152R PCDHGA12  原钙粘蛋白γA12抗体

hz-11153R PCDHB12  原钙粘蛋白β12抗体

hz-11154R PCDHB3  原钙粘蛋白β3抗体

hz-11155R PCDHGB1  原钙粘蛋白γB1抗体

hz-3977R Aspartate Aminotransferase  谷草转氨酶抗体

hz-11156R PCDHGB2  原钙粘蛋白γB2抗体

hz-11157R PCDHGB4  原钙粘蛋白γB4抗体

hz-11158R PCDHGB6  原钙粘蛋白γB6抗体

hz-11159R PCDHGC3/PCDH2  原钙粘蛋白γC3抗体