细胞表面趋化因子受体5抗体

英文名称    CCR5    

中文名称    细胞表面趋化因子受体5抗体    

别    名    C-C chemokine receptor 5; CCR5; CC-CKR-5;CCR-5; CCCKR5; CD195; CD 195; CKR-5; CKR5; CMKBR5; FLJ78003; IDDM22; AM4-7; C C chemokine receptor type 5; C-C motif chemokine receptor 5 A159A; CC Chemokine Receptor Type 5; CCR5 chemokine (C C motif) receptor 5; Chemokine receptor CCR5; CHEMR13; HIV 1 Fusion Coreceptor; HIV1 fusion coreceptor; IDDM22; MIP-1 alpha receptor; CCR5_HUMAN.    

说 明 书    0.1ml  0.2ml  1ml    

研究领域    细胞生物  免疫学  细胞膜受体  细胞表面分子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞表面趋化因子受体5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    40kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CCR-5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞表面趋化因子受体5抗体产品介绍    background:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Function:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.    

细胞表面趋化因子受体5抗体

hz-0403R-AF647 Rabbit anti-MG IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗长爪沙鼠IgG

hz-0403R-PE-hzy5.5 Rabbit anti-MG IgG/PE-Cy5.5  PE-Cy5.5标记的兔抗长爪沙鼠IgG

hz-0403R-AP Rabbit anti-MG IgG/AP  碱性磷酸酶（AP）标记的兔抗长爪沙鼠IgG

hz-0403R-Gold Rabbit anti-MG IgG/Gold  胶体金标记的兔抗长爪沙鼠IgG

hz-0403R-HRP Rabbit anti-MG IgG/HRP  辣根过氧化物酶标记的兔抗长爪沙鼠IgG

hz-0777R-HRP Rabbit Anti-Mink IgG/HRP  辣根过氧化物酶标记的兔抗水貂IgG

hz-0777R-hzy3 Rabbit Anti-Mink IgG/Cy3  Cy3标记的兔抗水貂IgG

hz-0777R-hzy5 Rabbit Anti-Mink IgG/Cy5  Cy5标记的兔抗水貂IgG

hz-0777R-hzy5.5 Rabbit Anti-Mink IgG/Cy5.5  Cy5.5标记的兔抗水貂IgG

hz-0777R-hzy7 Rabbit Anti-Mink IgG/Cy7  Cy7标记的兔抗水貂IgG

hz-0777R-PE Rabbit Anti-Mink IgG/PE  PE标记的兔抗水貂IgG

hz-0777R-PE-hzy3 Rabbit Anti-Mink IgG/PE-Cy3  PE-Cy3标记的兔抗水貂IgG

hz-0777R-PE-hzY5 Rabbit Anti-Mink IgG/PE-CY5  PE-CY5标记的兔抗水貂IgG

hz-0777R-APhz Rabbit Anti-Mink IgG/APC  APC标记的兔抗水貂IgG

hz-0777R-AF350 Rabbit Anti-Mink IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗水貂IgG

hz-0777R-AF488 Rabbit Anti-Mink IgG/Alexa Fluor 488  Alexa Fluor 488标记的兔抗水貂IgG

hz-0777R-AF555 Rabbit Anti-Mink IgG/Alexa Fluor 555  Alexa Fluor 555标记的兔抗水貂IgG

hz-0777R-AF647 Rabbit Anti-Mink IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗水貂IgG

hz-0777R-PE-hzy5.5 Rabbit Anti-Mink IgG/PE-Cy5.5  PE-Cy5.5标记的兔抗水貂IgG

hz-0777R-PE-hzy7 Rabbit Anti-Mink IgG/PE-Cy7  PE-Cy7标记的兔抗水貂IgG

hz-0777R-AP Rabbit Anti-Mink IgG/AP  碱性磷酸酶（AP）标记的兔抗水貂IgG

hz-0777R-Gold Rabbit Anti-Mink IgG/Gold  胶体金标记的兔抗水貂IgG

hz-0777R-Bio Rabbit Anti-Mink IgG/Bio  生物素标记的兔抗水貂IgG

hz-0777R-FIThz Rabbit Anti-Mink IgG/FITC  FITC标记的兔抗水貂IgG

hz-0777R-RBIThz Rabbit Anti-Mink IgG/RBITC  罗丹明标记的兔抗水貂IgG

hz-0297D-RBIThz Donkey Anti-human IgG/RBITC  罗丹明标记的驴抗人IgG

hz-0297D-Gold Donkey Anti-human IgG/Gold  胶体金标记的驴抗人IgG

hz-0297D-FIThz Donkey Anti-human IgG/FITC  FITC标记的驴抗人IgG

hz-0297D-hzy3 Donkey Anti-human IgG/Cy3  Cy3标记的驴抗人IgG

hz-0297D-hzy5 Donkey Anti-human IgG/Cy5  Cy5标记的驴抗人IgG