磷酸化CBX5抗体

英文名称    Phospho-CBX5 (Tyr37)    

中文名称    磷酸化CBX5抗体    

别    名    Antigen p25; Cbx 5; Cbx5; CBX5_HUMAN; CG8409; Chromobox homolog 5 (Drosophila HP1 alpha); Chromobox homolog 5 (HP1 alpha homolog Drosophila); Chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox homolog 5; HP1 alpha homolog; Chromobox protein homolog 5; Chromobox protein homologue 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1; HP 1; HP 1A; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha; Su(var)205; HP1a; HP1Hs-alpha; HP1 alpha; Antigen p25; Heterochromatin protein 1 homolog alpha.    

说 明 书    0.2ml      

产品类型    磷酸化抗体     

研究领域    染色质和核信号  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化CBX5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    22kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human CBX5 around the phosphorylation site of Tyr37    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化CBX5抗体产品介绍    background:

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].

Function:
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.     

磷酸化CBX5抗体

hz-0368G-hzy5.5 Goat Anti-Mouse IgM/Cy5.5  Cy5.5标记的羊抗小鼠IgM

hz-0368G-hzy7 Goat Anti-Mouse IgM/Cy7  Cy7标记的羊抗小鼠IgM

hz-0368G-PE Goat Anti-Mouse IgM/PE  PE标记的羊抗小鼠IgM

hz-0368G-PE-hzy3 Goat Anti-Mouse IgM/PE-Cy3  PE-Cy3标记的羊抗小鼠IgM

hz-0368G-PE-hzY5 Goat Anti-Mouse IgM/PE-CY5  PE-CY5标记的羊抗小鼠IgM

hz-0368G-APhz Goat Anti-Mouse IgM/APC  APC标记的羊抗小鼠IgM

hz-0368G-AF350 Goat Anti-Mouse IgM/Alexa Fluor 350  Alexa Fluor 350标记的羊抗小鼠IgM

hz-0368G-AF488 Goat Anti-Mouse IgM/Alexa Fluor 488  Alexa Fluor 488标记的羊抗小鼠IgM

hz-0368G-AF555 Goat Anti-Mouse IgM/Alexa Fluor 555  Alexa Fluor 555标记的羊抗小鼠IgM

hz-0368G-AF647 Goat Anti-Mouse IgM/Alexa Fluor 647  Alexa Fluor 647标记的羊抗小鼠IgM

hz-0368G-PE-hzy5.5 Goat Anti-Mouse IgM/PE-Cy5.5  PE-Cy5.5标记的羊抗小鼠IgM

hz-0368G-PE-hzy7 Goat Anti-Mouse IgM/PE-Cy7  PE-Cy7标记的羊抗小鼠IgM

hz-0368G-AP Goat Anti-Mouse IgM/AP  碱性磷酸酶（AP）标记的羊抗小鼠IgM

hz-0368G-Gold Goat Anti-Mouse IgM/Gold  胶体金标记的羊抗小鼠IgM

hz-0368G-Bio Goat Anti-Mouse IgM/Bio  生物素标记的羊抗小鼠IgM

hz-0368G-HRP Goat Anti-Mouse IgM/HRP  辣根过氧化物酶标记的羊抗小鼠IgM

hz-0293G-hzy3 Goat Anti-rat IgG/Cy3  Cy3标记的羊抗大鼠IgG

hz-0293G-hzy5 Goat Anti-rat IgG/Cy5  Cy5标记的羊抗大鼠IgG

hz-0293G-hzy5.5 Goat Anti-rat IgG/Cy5.5  Cy5.5标记的羊抗大鼠IgG

hz-0293G-hzy7 Goat Anti-rat IgG/Cy7  Cy7标记的羊抗大鼠IgG

hz-0293G-PE Goat Anti-rat IgG/PE  PE标记的羊抗大鼠IgG

hz-0293G-PE-hzy3 Goat Anti-rat IgG/PE-Cy3  PE-Cy3标记的羊抗大鼠IgG

hz-0293G-PE-hzY5 Goat Anti-rat IgG/PE-CY5  PE-CY5标记的羊抗大鼠IgG

hz-0293G-APhz Goat Anti-rat IgG/APC  APC标记的羊抗大鼠IgG

hz-0293G-AF350 Goat Anti-rat IgG/Alexa Fluor 350  Alexa Fluor 350标记的羊抗大鼠IgG

hz-0293G-AF488 Goat Anti-rat IgG/Alexa Fluor 488  Alexa Fluor 488标记的羊抗大鼠IgG

hz-0293G-PE-hzy5.5 Goat Anti-rat IgG/PE-Cy5.5  PE-Cy5.5标记的羊抗大鼠IgG

hz-0293G-PE-hzy7 Goat Anti-rat IgG/PE-Cy7  PE-Cy7标记的羊抗大鼠IgG

hz-0293G-Bio Goat Anti-rat IgG/Bio  生物素标记的羊抗大鼠IgG

hz-0293G-RBIThz Goat Anti-rat IgG/RBITC  罗丹明标记的羊抗大鼠IgG