细胞角蛋白2抗体

英文名称    Cytokeratin 2    

中文名称    细胞角蛋白2抗体    

别    名    CK2; Cytokeratin 2; KRT2B; keratin 76; CK 2P; CK2P; Cytokeratin 2P; Cytokeratin2; Cytokeratin2P; HUMCYT 2A; HUMCYT2A; K2P; Keratin 2p; Keratin 76; Keratin type II cytoskeletal 2 ora; Keratin2p; Keratin76; KRT 2B;KRT 2P; KRT 76; KRT2B; KRT2P; KRT76; K22O_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  信号转导  细胞类型标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞角蛋白2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    66kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CK2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞角蛋白2抗体产品介绍    background:

Keratins are a group of water-insoluble proteins that form monofilaments, a class of intermediate filament. These filaments form part of the cytoskeletal complex in epidermis and in most other epithelial tissues. Nineteen human epithelial keratins are resolved with two-dimensional gels electrophoresis (1). These can be divided into acid (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50’, 48, 46, 45 and 40 kD. The basic keratins have molecular weights of 65-67, 64, 59, 58, 56 and 52kD. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state (2-4). The 56.5/65-67kD pair is present in keratinized (differentiated) epidermis. The 55/64kD pair is characteristic of normal (corneal-type) epithelial differentiation (1,2). The 51/59kD pair is characteristic of the stratified squamous epithelial of internal organism such as esophagus and tongue (1,3). The 51/58kD pair is a keratinocyte marker; this pair is present in almost all stratified epithelia irrespective of the state of cellular stratification (1,2). The 48/56kD pair is characteristic of hyperproliferative (de-differentiated) keratinocytes (1,5). The 45/52kD pair and to a lesser extent, the 46/54kD pair are characteristic of simple epithelia (1). The 40kD keratin is present in most epithelia except adult epidermis (1).

Function:
Probably contributes to terminal cornification.    

细胞角蛋白2抗体

hz-1210R BRCA2  乳腺癌易感基因2抗体

hz-0489R BrdU  溴脱氧尿苷抗体

hzm-0917M BrdU(A7)  溴脱氧尿苷单克隆抗体

hz-0917R BrdU  溴脱氧尿苷抗体

hz-3669R BRN3A  转录因子Brn3蛋白抗体Brn3α

hz-3668R Brs3/Bombesin Receptor 3  蛙皮素受体3抗体

hz-1408R SMARCA4/SNF2 beta/BRG1  抑癌基因SNF2β抗体

hz-1015R BRMS-1  乳腺癌转移抑制基因1抗体

hz-2229R Brucella  布氏杆菌菌体蛋白抗体

hz-0292R BSA/Bovine Serum Albumin  牛血清白蛋白抗体

hz-1954R BSEP/ABCB11  胆汁酸盐输出泵蛋白抗体

hz-2668R Bone sialoprotein  骨涎蛋白抗体

hz-0031R BTG2/TIS21  B细胞迁移基因2抗体

hz-2752R BTK/ATK  蛋白酪氨酸激酶ATK抗体

hz-3055R Phospho-Btk(Ser180)  磷酸化蛋白酪氨酸激酶ATK抗体

hz-3069R Phospho-BTK/BPK(Tyr223)  磷酸化蛋白酪氨酸激酶ATK抗体

hz-3820R BAP135/TFII I  蛋白酪氨酸激酶BAP135抗体

hz-4179R RAD9  细胞周期检查控制蛋白质抗体

hz-5642R phospho-RAD9(Ser272)  磷酸化细胞周期检查控制蛋白质抗体

hz-5643R phospho-RAD9(Ser277)  磷酸化细胞周期检查控制蛋白质抗体

hz-5654R phospho-RAD9(Ser328)  磷酸化细胞周期检查控制蛋白质抗体

hz-5655R phospho-RAD9(Ser336)  磷酸化细胞周期检查控制蛋白质抗体

hz-5656R phospho-RAD9(Ser375)  磷酸化细胞周期检查控制蛋白质抗体

hz-5657R phospho-RAD9(Ser380)  磷酸化细胞周期检查控制蛋白质抗体

hz-5658R phospho-RAD9(Ser387)  磷酸化细胞周期检查控制蛋白质抗体

hz-5659R phospho-RAD9(Tyr28)  磷酸化细胞周期检查控制蛋白质抗体

hz-5677R phospho-RAD51(Thr310)  磷酸化Rad51抗体

hz-5678R Phospho-RSK2(Ser369)  磷酸化核糖体S6激酶RSK2抗体

hz-0324R C5a  过敏毒素C5a（补体C5a）抗体

hz-2934R C3  过敏毒素C3（补体C3）抗体

hz-0367G human C3  补体C3抗体

hz-2673R C5b-9  末端补体复合物抗体