促进凋亡基因抗体

英文名称    CIDEB    

中文名称    促进凋亡基因抗体    

别    名    cell death activator CIDE-B; cell death-inducing DFFA-like effector B; Cide-b; CIDEB_HUMAN.    

说 明 书    0.2ml      

研究领域    肿瘤  信号转导  细胞凋亡  转运蛋白  结合蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 促进凋亡基因抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    24kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CIDE-B C-terminus    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

促进凋亡基因抗体产品介绍    background:

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow.

Function:
Activates apoptosis.    

促进凋亡基因抗体

hz-2471R ICOS-L/B7-H2/CD275  诱导协同刺激分子配体CD275抗体

hz-5410R phospho-LEO1(Ser551)  磷酸化RNA聚合酶相关蛋白LEO1抗体

hz-4661R ICOS-L/B7-H2/CD275  诱导协同刺激分子配体CD275抗体

hz-4164R CT054/C20orf54  核黄素转运蛋白2抗体

hz-4229R ZDHHC21  γ-氨基丁酸A受体相关膜蛋白3

hz-4119R ASGPR1/ASGR1  唾液酸糖蛋白受体1抗体

hz-4242R ITPR1  5-三磷酸肌醇受体1抗体

hz-4126R GPI  糖磷脂酰肌醇抗体

hz-0673R B7H4  B7-H4抗体

hz-4243R ITPR2  5-三磷酸肌醇受体2抗体

hz-5040R BAAT  长链脂肪酸酰基辅酶A水解酶抗体

hz-4121R Exendin 4  GLP1类似蛋白Exendin4抗体

hz-0164R BACE1/ASP2  β分泌酶抗体

hz-5215R phospho-BACE1(Ser498)  磷酸化β分泌酶抗体

hz-5216R Phospho-Bad(Ser118)  磷酸化相关死亡促进因子抗体

hz-5217R Phospho-Bad(Ser134)  磷酸化相关死亡促进因子抗体

hz-5219R phospho-BAD(Ser99)  磷酸化相关死亡促进因子抗体

hz-0892R Bad  相关死亡促进因子Bad抗体

hz-0893R phospho-BAD(Ser128)  磷酸化相关死亡促进因子抗体

hz-3056R Phospho-Bad(Ser136)  磷酸化相关死亡促进因子抗体

hz-3057R Phospho-Bad(Ser155)  磷酸化相关死亡促进因子抗体

hz-1304R Bad  相关死亡促进因子Bad抗体

hz-3040R Phospho-Bad(Ser112)  磷酸化相关死亡促进因子抗体

hz-3009R phospho-BAD(Ser75)  磷酸化相关死亡促进因子抗体

hz-5799R BAG3  Bcl2抑凋亡蛋白Bag3抗体

hz-5134R BAG2  Bcl-2结合抑凋亡蛋白2抗体

hz-3664R Bag1/RAP46  抑凋亡基因bag1抗体

hz-1284R Bak  Bcl-2同源拮抗剂抗体

hz-0612R BADH2  BADH2抗体(水稻)

hz-4513R Transketolase(NT)  转酮醇酶(转羟乙醛酶)抗体（N端）

hz-4514R Transketolase(CT)  转酮醇酶(转羟乙醛酶)抗体（C端）

hz-4245R LONP1  线粒体离子肽酶1抗体

hz-5528R FXR1  脆性X相关蛋白1抗体

hz-0275R ZNF231/Bassoon  锌指蛋白231抗体