c-fos抗体

英文名称    c-fos    

中文名称    c-fos抗体    

别    名    Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus; FOS; FOS protein; G0 G1 switch regulatory protein 7; G0S7; Oncogene FOS; Proto oncogene protein c fos; v fos FBJ murine osteosarcoma viral oncogene homolog; FOS; AP-1; C-FOS; p55; FOS_HUMAN; Proto-oncogene c-Fos; G0/G1 switch regulatory protein 7.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  免疫学  神经生物学  信号转导  转录调节因子  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 c-fos抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    41kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human c-fos    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

c-fos抗体产品介绍    background:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].

Function:
Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation.    

c-fos抗体

hz-11120R PCDHA9  原钙粘附蛋白α9抗体

hz-5366R phospho-GNA12(Ser68)  磷酸化鸟苷酸调节蛋白12抗体

hz-11121R PCDHA7  原钙粘附蛋白α7抗体

hz-11122R PCDHA8  原钙粘附蛋白α8抗体

hz-11123R PCDHA10/CNRN8  钙粘蛋白相关神经受体8抗体

hz-2586R ASIC1/BNaC2  酸敏感离子通道1抗体

hz-11124R PCDHA11  原钙粘蛋白11抗体

hz-11125R ROM1  视网膜感光细胞外节膜蛋白1抗体

hz-11126R PVRL1/CD111/Nectin1  脊髓灰质炎受体相关蛋白1抗体

hz-11127R CD11b/c equivalent  CD11B/CD11C抗体

hz-11128R CASPR/Neurexin4  轴突蛋白4/少突胶质细胞抗体

hz-11129R Caspr2  轴突相关CNTP2蛋白抗体（少突胶质细胞）

hz-11130R VAT1L/KIAA1576  突触小泡膜蛋白同源样蛋白1抗体

hz-1282R ASPP1  p53凋亡刺激蛋白1抗体

hz-11131R LALBA/alpha Lactalbumin  乳清蛋白α抗体

hz-11132R Lamin B2  核纤层蛋白B2抗体

hz-11133R PCDHAC2  原钙粘蛋白介导的PCDHαC2受体抗体

hz-11134R PCDHB15/PCDHB22  原钙粘蛋白15抗体

hz-11135R PCDHB16  原钙粘蛋白16抗体

hz-11136R PCDHB2  原钙粘蛋白β2抗体

hz-11138R PCDHB4  原钙粘蛋白β4抗体

hz-11139R PCDHB5  原钙粘蛋白β5抗体

hz-11140R PCDHB7  原钙粘蛋白β7抗体

hz-11141R PCDHGA1  原钙粘蛋白γA1抗体

hz-11143R PCDHGA10  原钙粘蛋白γ10抗体

hz-11144R PCDHGA4  原钙粘蛋白γA4抗体

hz-11145R PCDHGA2  原钙粘蛋白γA2抗体

hz-11146R PCDHGA3  原钙粘蛋白γA3抗体

hz-11147R PCDHGA5  原钙粘蛋白γA5抗体

hz-11148R PCDHGA7  原钙粘蛋白γA7抗体

hz-11149R PCDHGA8  原钙粘蛋白γA8抗体

hz-11150R PCDHGA9  原钙粘蛋白γA9抗体