周期素依赖性激酶5抗体

英文名称    CDK5    

中文名称    周期素依赖性激酶5抗体    

别    名    Cdk 5; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  染色质和核信号  神经生物学  信号转导  细胞周期蛋白  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 周期素依赖性激酶5抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    32kDa    

细胞定位    细胞核 细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CDK5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

周期素依赖性激酶5抗体产品介绍    background:

CDK5 is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression.
CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.    

周期素依赖性激酶5抗体

hz-3048R Phospho-beta-Arrestin 1(Ser412)  磷酸化β抑制蛋白1抗体

hz-1332R β-arrestin/ARRB2  β-抑制蛋白2抗体/β休止蛋白2抗体

hz-0801R ARIP2B  激活素受体2B抗体

hz-5027R ARP4  肝血管生成素相关蛋白抗体

hz-4006R ARSA  芳基硫酸酯酶A抗体

hz-0055R Arthzin  Arthzin抗体

hz-0600R ADRA1/ADRA1B/alpha 1 Adrenergic Receptor  alpha 1肾上腺素能受体抗体

hz-11001R FAM61B/LSM14B  FAM61B蛋白抗体

hz-11002R ESYT1/FAM62A  延伸突触蛋白1抗体

hz-11003R ESYT2/FAM62B  延伸突触蛋白2抗体

hz-11004R FAM63A  FAM63A蛋白抗体

hz-11005R RCS1/FAM64A  染色体分离调节蛋白1抗体

hz-11006R FAM70A  FAM70A蛋白抗体

hz-11007R FAM71A  FAM71A蛋白抗体

hz-11008R FAM71A  FAM71A蛋白抗体

hz-11009R FAM83F  FAM83F蛋白抗体

hz-11010R NSE1/FAM84A  感觉神经蛋白1抗体

hz-11011R FAM92A1  FAM92A1蛋白抗体

hz-11012R FAM98A  FAM98A蛋白抗体

hz-11013R ILDR1  免疫球蛋白样结构域受体1抗体

hz-11014R ILVBL  乙酰乳酸合成酶蛋白抗体

hz-11015R BFSP2/Phakinin  晶状体蛋白2抗体

hz-11016R GFAP delta  胶质纤维酸性蛋白GFAPδ抗体

hz-11017R NPTX2  神经细胞穿透素2抗体

hz-11019R CD276/B7H3  CD276抗体

hz-11021R CRIPT  突触后蛋白CRIPT抗体

hz-11022R DNAH10  轴丝动力蛋白10抗体

hz-11023R DNAH7  轴丝动力蛋白7抗体

hz-11024R DNAI1/Dynein intermediate chain 1  轴丝中链动力蛋白抗体

hz-11025R Gigaxonin  巨轴索神经病蛋白GAN抗体

hz-11026R Kinesin  驱动蛋白KNS1抗体

hz-11027R KIF5A/NKHC1  驱动蛋白KIF5A抗体

hz-11028R MAP1B  微管相关蛋白1B抗体