周期素依赖性激酶1抗体

英文名称    CDK1    

中文名称    周期素依赖性激酶1抗体    

别    名    Cdc 2; Cdc2; CDK 1; CDK1; Cell division control protein 2; Cell division control protein 2 homolog; PSTAIR; Cell division cycle 2 G1 to S and G2 to M; Cell Divsion Cycle 2 Protein; Cyclin Dependent Kinase 1; DKFZp686L20222; MGC111195; p34 Cdk1; p34 Protein Kinase.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  信号转导  细胞周期蛋白  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Bovine,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 周期素依赖性激酶1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    34kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CDK1 C-terminus    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

周期素依赖性激酶1抗体产品介绍    background:

The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.    

周期素依赖性激酶1抗体

hz-9936R C11orf21  11号染色体开放阅读框21抗体

hz-9937R C11orf24  11号染色体开放阅读框24抗体

hz-9938R C11orf53  11号染色体开放阅读框53抗体

hz-9939R C11orf57  11号染色体开放阅读框57抗体

hz-9940R C11orf65  11号染色体开放阅读框65抗体

hz-9941R C11orf71  11号染色体开放阅读框71抗体

hz-9942R C11orf73  11号染色体开放阅读框73抗体

hz-9943R C11orf74  11号染色体开放阅读框74抗体

hz-9944R C12ORF4  12号染色体开放阅读框4抗体

hz-9945R C12ORF24  12号染色体开放阅读框24抗体

hz-9946R C12ORF29  12号染色体开放阅读框29抗体

hz-9947R C12ORF40  12号染色体开放阅读框40抗体

hz-9948R C12ORF42  12号染色体开放阅读框42抗体

hz-9949R C12ORF49  12号染色体开放阅读框49抗体

hz-5214R phospho-AQP2(Ser261)  磷酸化水通道蛋白2抗体

hz-5185R phospho-AQP2(Ser264)  磷酸化水通道蛋白2抗体

hz-9950R C12ORF50  12号染色体开放阅读框50抗体

hz-1253R AQP3  水通道蛋白-3抗体

hz-9951R C12ORF53  12号染色体开放阅读框53抗体

hz-9952R C12ORF54  12号染色体开放阅读框54抗体

hz-5187R phospho-AQP2(Ser269)  磷酸化水通道蛋白2抗体

hz-9953R C12ORF61  12号染色体开放阅读框61抗体

hz-9954R C12ORF63  12号染色体开放阅读框63抗体

hz-9955R C12ORF68  12号染色体开放阅读框68抗体

hz-9956R CRCT1  富含半胱氨酸C端蛋白1抗体

hz-9957R CREG2  E1A激活基因刺激蛋白2抗体

hz-9958R CWF19L1  CWF19L1蛋白抗体

hz-9959R CWH43  细胞壁合成蛋白43抗体

hz-9960R Cactin/C19orf29  19号染色体开放阅读框29抗体

hz-9961R MMAA/cblA  甲基丙二酸尿症cblA抗体

hz-9971R CREPT  肿瘤高表达细胞周期相关蛋白抗体