白细胞分化抗原CD2AP抗体

英文名称    CD2AP    

中文名称    白细胞分化抗原CD2AP抗体    

别    名    CD2-associated protein; Adapter protein CMS; AL024079; Cas ligand with multiple SH3 domains; C78928; Cd2ap; CMS; Mesenchyme to epithelium transition protein with SH3 domains 1; METS 1; Mets1; CD2AP_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    信号转导  转运蛋白  结合蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 白细胞分化抗原CD2AP抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    71kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CD2AP    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

白细胞分化抗原CD2AP抗体产品介绍    background:

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008].

Function:
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.    

白细胞分化抗原CD2AP抗体

hz-7819R NUP37  核孔蛋白Nup37抗体

hz-7820R PARD6B  缺陷性分配同源物β抗体

hz-7821R PELO  PELO蛋白抗体

hz-7822R POC5  细胞中心粒蛋白抗体

hz-7823R POLA2  DNA聚合酶α2抗体

hz-7824R PSF2  PSF2蛋白抗体

hz-7825R PTOP  肾上腺皮质发育异常同源蛋白抗体

hz-7826R RABGAP1  Rab蛋白GTP酶激活蛋白1抗体

hz-7827R RCL/c Myc responsive  c-Myc应答蛋白抗体

hz-7828R RINT1  胞膜间内质网调节蛋白1抗体

hz-7829R RMND1  减数分裂同源蛋白1抗体

hz-7830R SGTA  小谷氨酰胺三角四肽重复区蛋白α抗体

hz-7831R SUGT1  SUGT1蛋白抗体

hz-7832R APC6/CDC16  细胞分裂周期蛋白16抗体

hz-7833R phospho-APC6/CDC16(Ser560)  磷酸化细胞分裂周期蛋白16抗体

hz-7834R Borealin/CDCA8  细胞分裂周期蛋白8抗体

hz-7835R Bub3  有丝分裂蛋白BUB3抗体

hz-7836R Dynamitin/DCTN2  动力蛋白激活蛋白2抗体

hz-7837R EB2/End binding protein 2  微管相关末端结合蛋白2抗体

hz-7838R INSC  有丝分裂相关蛋白INSC抗体

hz-7839R CENPF  有丝分裂着丝粒蛋白F抗体

hz-7840R Mad2L2  有丝分裂阻滞缺陷2样蛋白2抗体

hz-7841R NUDC  细胞核分离基因C蛋白抗体

hz-7842R phospho-NUDC(Ser326)  磷酸化细胞核分离基因C蛋白抗体

hz-7843R NUP160  核孔蛋白NUP160抗体

hz-7844R Ninein/GSK3B interacting protein  GSK3B相互作用蛋白抗体

hz-7845R RASSF7  RAS家族关联结构域蛋白7抗体

hz-7846R SKA1  纺锤体和着丝粒相关蛋白1抗体

hz-7847R SKA2  纺锤体和着丝粒相关蛋白2抗体

hz-7848R SKA3  纺锤体和着丝粒相关蛋白3抗体

hz-7849R TBCD/Beta tubulin cofactor D  微管蛋白β辅助因子D抗体

hz-7850R MPS1/TTK  单极纺锤体蛋白激酶1抗体

hz-7851R katanin p80  剑蛋白p80抗体

hz-7852R ZWINT  着丝粒ZW10相互作用蛋白1抗体