非受体酪氨酸激酶c-Abl抗体

英文名称    c-Abl    

中文名称    非受体酪氨酸激酶c-Abl抗体    

别    名    Abelson Murine Leukemia Viral Oncogene Homolog 1; Abelson murine leukemia viral v abl oncogene homolog 1; Abl 1; ABL; Abl1; Abl protein; Abl1; Bcr/c abl oncogene protein; JTK 7; JTK7; p150; Proto oncogene tyrosine protein kinase ABL1; Transformation gene oncogene ABL; v abl Abelson murine leukemia viral oncogene homolog 1; v abl; ABL1_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  免疫学  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶  线粒体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 非受体酪氨酸激酶c-Abl抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    124kDa    

细胞定位    细胞核 细胞浆 细胞膜 线粒体    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human c-Abl (393-442aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

非受体酪氨酸激酶c-Abl抗体产品介绍    background:

The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].    

非受体酪氨酸激酶c-Abl抗体

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hz-7594R Ankyrin erythroid  红细胞蛋白Ank1抗体

hz-7595R PPM1F  钙调蛋白依赖性蛋白激酶磷酸酶抗体

hz-7596R RIP3  受体结合丝氨酸苏氨酸激酶3抗体

hz-7597R RIP5/RIPK5  受体结合丝氨酸苏氨酸激酶5抗体

hz-7598R SPHK2  鞘氨醇激酶2抗体

hz-7599R STK3  丝氨酸/苏氨酸蛋白激酶3抗体

hz-7600R IKIP  IKK激酶相互作用蛋白抗体

hz-0840R AMACR/P504S  α-甲基酰基辅酶A消旋酶抗体

hz-4097R CASC3/MLN51  肿瘤易感候选基因3抗体

hz-7601R phospho-IKKi/IKKe(Thr500)  磷酸化核因子NFκB抑制蛋白激酶i抗体

hz-7602R TIAF1  TGFB1诱导抗凋亡因子1抗体

hz-7603R Cipar1  前列腺雄激素抑制信号蛋白1抗体

hz-7604R Apoptosis enhancing nuclease  细胞凋亡增强核酸酶抗体

hz-7605R Cell death inducing protein/C16orf5  细胞死亡诱导蛋白抗体

hz-5283R phospho-CASC3(Tyr181)  磷酸化肿瘤易感候选基因3抗体

hz-7606R CYFIP2  细胞质脆性X智力低下蛋白结合蛋白2抗体

hz-7607R CSNK1D  酪蛋白激酶δ1抗体

hz-7608R CDC14B  细胞分裂周期蛋白14B抗体

hz-7609R DUSP2  双特异性磷酸酶2抗体

hz-7610R ETHE1  乙基丙二酸脑病蛋白抗体

hz-7611R GTSE1/G2 and S phase expressed 1  G2期/S期应答相关蛋白1抗体

hz-7612R HIPK4  同源相互作用蛋白激酶4抗体

hz-3830R AMBRA1  自噬相关基因AMBRA1抗体

hz-7613R IBRDC2/RNF144B  E3泛素蛋白连接酶144B抗体（环指蛋白144B）

hz-7614R JMY  连接介导调节蛋白抗体

hz-7615R LRDD/PIDD  富含亮氨酸重复死亡结构域蛋白抗体

hz-7616R MCG10  RNA相关结合蛋白MCG10抗体

hz-7617R NME6/IPIA ALPHA  P53诱导细胞凋亡抑制蛋白α抗体

hz-7618R NOC2L  NOC2家族样蛋白抗体