BATF2蛋白抗体

英文名称    BATF2    

中文名称    BATF2蛋白抗体    

别    名    B ATF 2; Basic leucine zipper transcriptional factor ATF like 2; BATF2; BATF2_HUMAN; MGC20410; SARI; Suppressor of AP 1 regulated by IFN.    

说 明 书    0.2ml      

研究领域    细胞生物  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 BATF2蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    29kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BATF2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

BATF2蛋白抗体产品介绍    background:

BATF2 is a 274 amino acid protein that localizes to the nucleus and contains one bZIP domain, suggesting that it may be involved in transcriptional regulation. The gene encoding BATF2, which is expressed as multiple alternatively spliced isoforms, is located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Function:
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes By similarity. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.    

BATF2蛋白抗体

hz-7534R PGC1 beta  过氧化物酶体增殖物激活受体γ辅激活子1β抗体

hz-7535R PGC1 alpha + beta  过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体

hz-7536R SERPINA12/Vaspin  内脏脂肪组织源性丝氨酸蛋白酶抑制蛋白抗体

hz-7537R SIRT4/SIR 2 like protein 4  沉默调节相关蛋白4抗体

hz-7538R TRIB3/p65 interacting inhibitor of NF-kappaB  神经细胞死亡诱导蛋白激酶抗体

hz-7539R SERCA1 ATPase  肌浆/内质网钙ATP酶1抗体

hz-7540R GRK5  G蛋白偶联受体激酶5抗体

hz-7541R EDG3  内皮分化型G蛋白偶联受体3抗体

hz-7551R TNFAIP3 interacting protein 3/ABIN3  肿瘤坏死因子α诱导相互作用蛋白3抗体

hz-7542R RISC/Serine carboxypeptidase 1  丝氨酸羧肽酶1抗体

hz-2731R APS  APS抗体

hz-7544R SOAT1/ACAT1  胆固醇酰基转移酶1抗体

hz-3003R phospho-APS(Ser598)  磷酸化APS抗体

hz-7545R Scavenger Receptor BII  清道夫受体B2抗体

hz-7546R CD239  B细胞粘附分子CD239抗体

hz-3569R AP2 alpha  转录激活蛋白2α抗体

hz-7547R CPB2/Carboxypeptidase B2  胰羧肽酶B2抗体

hz-7548R Fibrinopeptide A  纤维蛋白肽A/血纤肽抗体

hz-7549R GAS 6  生长停滞特异性蛋白6抗体

hz-7550R AUP1/Ancient ubiquitous protein 1  原始广泛存在蛋白1抗体

hz-7552R Biglycan  骨/软骨蛋白多糖1抗体

hz-2532R ALT1  谷丙氨酸氨基转移酶1抗体

hz-7553R Eph receptor A2+A3+A4  内皮细胞受体蛋白酪氨酸激酶A2+A3+A4抗体

hz-7554R phospho-Eph receptor A2+A3+A4 (Tyr588 + Tyr596)  磷酸化内皮细胞受体蛋白酪氨酸激酶A2+A3+A4抗体

hz-7555R phospho-EPH A3+A4+A5 ( Tyr779)  磷酸化内皮细胞受体蛋白酪氨酸激酶A3+A4+A5抗体

hz-7556R FLAP/5-lipoxygenase activating protein  5脂氧合酶激活蛋白抗体

hz-7557R IKK alpha + IKK beta  KB抑制蛋白激酶α/β抗体

hz-7558R MC3 Receptor  黑素皮质素受体3抗体

hz-7559R PDGF AB+BB  血小板源性生长因子AB+BB抗体

hz-7560R CPLA2  胞浆型磷脂酶A2抗体

hz-7561R TIRAP  白细胞介素1受体衔接蛋白抗体