BRD3蛋白抗体

英文名称    BRD3    

中文名称    BRD3蛋白抗体    

别    名    BRD 3; Brd3; BRD3_HUMAN; Bromodomain containing 3; Bromodomain containing protein 3; Bromodomain-containing protein 3; KIAA0043; Open reading frame X; ORFX; RING3 like gene; RING3-like protein; RING3L.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  信号转导  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 BRD3蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    80kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BRD3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

BRD3蛋白抗体产品介绍    background:

The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Function:
Binds hyperacetylated chromatin and plays a role in theregulation of transcription, probably by chromatin remodeling andinteraction with transcription factors. Regulates transcription bypromoting the binding of the transcription factor GATA1 to itstargets (By similarity). Regulates transcription of the CCND1 gene.    

BRD3蛋白抗体

hz-6119R ZNF185  锌指蛋白185抗体

hz-6121R RBMX  糖蛋白P43抗体

hz-6123R PRB2/p130  视网膜母细胞瘤相关蛋白p130抗体

hz-6124R p95 NBS1/Cell cycle regulatory protein p95  细胞周期调节蛋白P95抗体

hz-6125R phospho-p95 NBS1(Ser343)  磷酸化滑膜细胞凋亡抑制物1抗体

hz-6126R FAM123B/AMER1  肾母细胞瘤X蛋白抗体

hz-6127R KARS2/Lysyl tRNA synthetase  赖氨酸tRNA的连接酶抗体

hz-6128R WSTF  转录因子WSTF抗体

hz-6129R Wnt8A  信号通路WNT8A抗体

hz-6133R WNT2  信号通路Wnt2抗体

hz-6137R CtIP/RBBP8  视网膜母细胞瘤结合蛋白8抗体

hz-6138R EID1  乙酰基转移酶EID1抗体

hz-6139R KDM5B/PLU1/Jarid1B  组蛋白去甲基化酶JARID1B抗体

hz-6140R KMT8/Riz1/Riz2  转录因子GATA3结合蛋白G3B抗体

hz-6141R GLIPR1  脑胶质瘤发病机制相关蛋白1抗体

hz-6142R RING1  环指蛋白1抗体

hz-6143R PIG3/TP53I3  p53诱导蛋白3抗体

hz-6144R PRMT4  组蛋白精氨酸甲基转移酶CARM1抗体

hz-6145R TP53I13  肿瘤蛋白p53诱导蛋白13(肿瘤抑制基因)

hz-6146R p53 DINP1  p53诱导核蛋白1抗体

hz-6147R p73 alpha  p53相关蛋白P73α抗体

hz-6148R Frizzled 1/Wnt receptor  Wnt信号受体蛋白抗体

hz-6149R GNAT3  G蛋白转录因子α3抗体

hz-6150R GPR124  G蛋白偶联受体124抗体（肿瘤血管内皮标记物）

hz-6151R GPR172B  G蛋白偶联受体172B抗体

hz-6152R GNAQ/Gα q  G蛋白α亚单位蛋白Q抗体

hz-6155R RAP1GDS1  G蛋白GTP-GDP解离刺激因子1抗体

hz-6156R RASGEF1A  鸟嘌呤核苷酸交换因子rasgef1a抗体